Hematology Flashcards
Is iron deficiency anemia micro or macrocytic
microcytic
What does it look like under a scope (Iron Anemia)
Small, pale red RBC
Clinical Features of Iron Anemia
Fatigue
Cognitive impairment
Tachycardia
Physical Findings of Iron ANemia
Spoon Nails
Pallor
Angular Cheileits
What causes Megaloblastic Anemia
B12 and Folic Acid Deficiency
Clincal features of Megaloblastic anemia
Weakness Anorexia Oral Ulcers Jaundice Bruising Fever Purpura Optic Nerve atrophy
What will lab results show for Megaloblastic Anemia
Macrocytic
Hypersegment Neutrophils
What causes sickle cell?
Two B Sickle Genes
What is Acute Lymphoblastic Leukemia (ALL)
Proliferation of immature T or B Cells that replace bone marrow cells
Who gets ALL?
Children
What is the prognosis
Rapidly fatal if not treated. Ok prognosis with chemo/marrow transplant
What is Acute Myeloid Leukemia (AML)
Prolideration of myeloblasts
What structure is unique to AML
Auer rods
Who gets AML
Adults
What is the WBC count in AML?
Variable
What is the prognosis in AML?
Fatal without treatment, poor even with treatment
What is Chronic Lyphocytic Leukemia
Proliferation of small lymphocytes with absolute lymphocytosis
Who gets CLL
Older people
What is Richter’s transformation
CLL turns into agressive lymphoma
What is Chronic Myeloid Leukemia
Proliferation of Stem cells
Who gets CML
Young to middle age
What city is the chromosome named after
Philly
What is the genetic abnormality that leads to CML
Translocation between 9 and 22
