Hematology Flashcards

1
Q

Is iron deficiency anemia micro or macrocytic

A

microcytic

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2
Q

What does it look like under a scope (Iron Anemia)

A

Small, pale red RBC

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3
Q

Clinical Features of Iron Anemia

A

Fatigue
Cognitive impairment
Tachycardia

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4
Q

Physical Findings of Iron ANemia

A

Spoon Nails
Pallor
Angular Cheileits

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5
Q

What causes Megaloblastic Anemia

A

B12 and Folic Acid Deficiency

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6
Q

Clincal features of Megaloblastic anemia

A
Weakness
Anorexia
Oral Ulcers
Jaundice
Bruising
Fever
Purpura
Optic Nerve atrophy
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7
Q

What will lab results show for Megaloblastic Anemia

A

Macrocytic

Hypersegment Neutrophils

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8
Q

What causes sickle cell?

A

Two B Sickle Genes

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9
Q

What is Acute Lymphoblastic Leukemia (ALL)

A

Proliferation of immature T or B Cells that replace bone marrow cells

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10
Q

Who gets ALL?

A

Children

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11
Q

What is the prognosis

A

Rapidly fatal if not treated. Ok prognosis with chemo/marrow transplant

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12
Q

What is Acute Myeloid Leukemia (AML)

A

Prolideration of myeloblasts

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13
Q

What structure is unique to AML

A

Auer rods

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14
Q

Who gets AML

A

Adults

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15
Q

What is the WBC count in AML?

A

Variable

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16
Q

What is the prognosis in AML?

A

Fatal without treatment, poor even with treatment

17
Q

What is Chronic Lyphocytic Leukemia

A

Proliferation of small lymphocytes with absolute lymphocytosis

18
Q

Who gets CLL

A

Older people

19
Q

What is Richter’s transformation

A

CLL turns into agressive lymphoma

20
Q

What is Chronic Myeloid Leukemia

A

Proliferation of Stem cells

21
Q

Who gets CML

A

Young to middle age

22
Q

What city is the chromosome named after

A

Philly

23
Q

What is the genetic abnormality that leads to CML

A

Translocation between 9 and 22