Hematology Flashcards
Hgb Norm
12.3-15.3 g/dL
Hct Norm
36-45%
MCV Norm
80-96 fL/cell
Macrocytic anemia range
MCV > 96
Caused by Vit B12 or folate deficiency
RDW Norm
11.5-14.5%
Increased RBC count is ______
Polycythemia
Decreased RBC count is ______
Anemia
Increased immature RBC count is _____
Reticulocytosis
Low hgb indicates:
Anemia
Low hct indicates:
Anemia
Increased RDW is due to:
Folate deficiency, Vit B12 deficiency, and iron deficiency
Reticulocyte Norm range
0.5-2.5%
High Reticulocyte count indicates:
RBC destruction/loss
Vit B12 deficiency diagnosis test
Schillings test
Causes of Vit B12 deficiency:
Dietary deficiency, intrinsic factor deficiency
Causes of Folic Acid deficiency:
Pregnancy, diet deficiency, “Celiac disease”
Decreased ferritin indicates:
Iron deficiency anemia
Serum iron decrease indicates:
Iron deficiency anemia and anemia of chronic disease
Serum iron increase indicates:
Hemolytic anemia
Increased TIBC indicates:
Iron deficiency anemia
Decreased percent iron saturation indicates:
Iron deficiency anemia and anemia of chronic disease
Ferritin levels are normal in ______
Anemia of chronic disease
Decreased TIBC indicates:
Anemia of chronic disease
Reticulocyte count is normal in ______ and ______
iron deficiency anemia of chronic disease
Normacytic anemia range and types:
80-96
Acute blood loss
Hemolytic anemia
Anemia of chronic disease
Coombs test is used to diagnose _______
Hemolytic anemia
High Reticulocyte count indicates:
Acute blood loss and hemolytic anemia
ESR Norm
1-20 mm/hr
Increased ESR (>20 mm/hr) indicates:
RA and SLE
WBC Norm
4.4-11.3 x 10^3 cells/microliter
Mature Neutrophil Norm (segs/PMNs)
45-73%
Immature neutrophil norm (“bands”)
3-5%
Eosinophil norm
0-4%
Basophil norm
0-1%
Monocytes and macrophage norm
2-8%
Lymphocyte norm
20-40%
Increased Neutrophil/band indicates:
Bacteria, TB, stressors, corticosteroids
Decreased neutrophils/bands due to:
Radiation
Increased lymphocytes due to:
Virus
Decreased lymphocytes due to:
HIV, corticosteroids, radiation
Increased eosinophils due to:
Parasites, allergies
Increased basophils due to:
TB, chronic infections
Plt norm
150,000-450,000 cells/microliter
Thrombocytopenia plt count
Less than 150,000 cells/microliter
Cause of hyperdestructive Thrombocytopenia
High MPV
Caused by drugs (heparin) and autoimmune disease (SLE)
Cause of hypoproductive Thrombocytopenia
Low MPV
Caused by aplastic anemia
Thrombocytosis plt count
> 450,000 cells/microliter
Causes of Thrombocytosis
Stress, infection, trauma, malignancy
MPV norm
7-11 fL
INR Normal range
0.9-1.2 (1.0)
Therapeutic INR normal range w/ warfarin
2-3
Antifactor Xa Assay used with _______
With heparin
D-dimer norm
Less than 0.5 mcg/mL
High d-dimer indicates:
Thromembolism (clot)
RBC Norm
4.1-5.1 x 10^6 cells/microliter
Microcytic anemia MCV range:
MCV less than 80