Diabetes Flashcards

1
Q

Type 2 DM age of onset

A

> 40 yo

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2
Q

Type 1 DM rapidity of onset

A

Abrupt

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3
Q

Type 2 DM rapidity of onset

A

Gradual

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4
Q

Type 1 DM body weight

A

Usually thin and undernourished

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5
Q

Type 2 DM body weight

A

Obesity is common

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6
Q

Does Type 1 DM have islet cell antibodies/ pancreatic cell-mediated immunity?

A

Yes

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7
Q

Does Type 2 DM have islet cell antibodies/ pancreatic cell-mediated immunity?

A

No

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8
Q

Is ketosis common in Type 1 DM or type 2 DM?

A

Type 1

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9
Q

Insulin levels in Type 1 DM

A

Diminished or totally absent

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10
Q

Insulin levels in Type 2 DM

A

Low, normal, or high (depends on insulin resistance)

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11
Q

Type 1 DM symptoms

A

Polyuria, polydipsia, polyphagia (3 Ps), weight loss

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12
Q

Type 2 DM symptoms

A

Asymptomatic or could have polyuria + polydipsia + polyphagia

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13
Q

C-peptide fasting range

A

0.78-1.89 ng/mL

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14
Q

C-peptide range 1 hour after glucose load

A

5-12 ng/mL

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15
Q

High levels of C-peptide indicate:

A

Type 2 DM

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16
Q

Low levels of C-peptide indicate:

A

Type 1 DM

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17
Q

Autoantibodies present indicate:

A

Type 1 DM

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18
Q

Normal FPG levels

A

Less than 100

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19
Q

Pre-diabetes FPG levels

A

100-125

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20
Q

DM FPG levels

A

> or = 126

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21
Q

Gestational DM FPG levels

A

> or = 92

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22
Q

Gestational DM OGTT value at 1 hr

A

> or = 180

23
Q

Normal OGTT value at 2 hr

A

Less than 140

24
Q

Pre-diabetes OGTT value at 2 hr

25
DM OGTT value at 2 hr
> or = 200
26
Gestational DM OGTT value at 2 hr
> or = 153
27
Normal A1C level
Less than 5.7%
28
Pre-diabetes A1C level
5.7-6.4%
29
DM A1C level
> or = 6.5%
30
Gestational DM A1C level
N/a
31
FPG test is best indicator for:
Glucose homeostasis
32
OGTT best for:
Screen/diagnose gestational diabetes
33
A1C best indicates:
Glucose control over past 3 months
34
Type 1 DM age of onset
Child hood or adolescence
35
Fructosamine normal range
Less than 285 micromol/L
36
Large quantities of fructosamine found in diabetics or non-diabetics?
diabetics
37
Urine glucose norm
Negative
38
Diabetic ketoacidosis (DKA) seen mostly in:
Type 1 DM
39
DKA causes:
Infections, illness, emotional stress, nonadherence/inadequate insulin dosage, undiagnosed type 1 DM
40
Signs of DKA:
Dehydration, lethargy, acetone-smelling breath, ab pain, tachycardia, orthostatic hypotension, tachypnea
41
Findings of DKA:
High glucose concentration, ketones present in blood/urine, low venous bicarbonate, decreased arterial pH, electrolyte abnormalities, elevated SCr & BUN, elevated serum osmolality
42
Hyperosmolar hyperglycemia state (HHS) occurs in:
most elderly patients w/ type 2 DM
43
Signs of HHS:
Decreased mentation (lethargy, confusion, dehydration), seizures, GI symptoms
44
Findings of HHS
Severe hyperglycemia, ABSENCE of ketones, electrolyte abnormalities, elevated SCr & BUN, elevated serum osmolality
45
Causes of hypoglycemia:
Excess blood glucose lowering meds, physical activity, inadequate carb intake
46
Hypoglycemia more common in type 1 or type 2 DM?
Type 1 DM
47
How to treat hypoglycemia
Rule of 15
48
ADA A1C goal:
Less than 7%
49
AACE A1C goal:
Less than or equal to 6.5%
50
ADA FPG goal:
80-130 mg/dL
51
AACE FPG goal:
Less than 110 mg/dL
52
ADA peak postprandial plasma glucose goal:
Less than 180 mg/dL
53
AACE peak postprandial plasma glucose goal:
Less than 140 mg/dL
54
Type 1 DM age of onset
Childhood or adolescence