hematology Flashcards

0
Q

anemia is always a ____ of another condition or disease

A

symptom

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1
Q

what is considered a low RBC count for men and women?

A

12 g/100ml women

14 g/100ml men

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2
Q

RBC pathology is either macrocytic or microcytic. Give examples of each

A

micro- iron deficiency

macro- b12 and folate

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3
Q

destruction of RBC most likely attributed to which two diseases

A

lupus and RA

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4
Q

decreased folic acid could be from what?

A

poor dietary intake, alcoholism and anorexia

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5
Q

_______ is a sex linked autosomal recessive trait

A

hemophilia

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6
Q

hemophilia A is lack of clotting factor __ which is found __ chromosome and produced by the liver

A

8, X

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7
Q

hemophilia incidence is

A

17,000 ppl/year

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8
Q

hemophilia occurs more frequently in men or women?

A

men

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9
Q

clotting factor 8 is important in the production of

A

thrombin

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10
Q

classification of hemophilia is based on % of clotting factor produced. what are these numbers

A

50-100% normal
6-30% mild
1-5% moderate
<1% severe

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11
Q

mild hemophilia

A

spontaneous bleeding is rare

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12
Q

moderate hemophilia

A

bleeding with mild trauma

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13
Q

severe hemophilia

A

severe bleeding common or with slight trauma

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14
Q

muscle hemorrhage occurs most in which muscle groups

A

flexor

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15
Q

main method of diagnosis of hemophilia

A

CBC

16
Q

sickle cell disease occurs in which molecule?

A

Hb S

17
Q

how many AA newborns have SCD?

A

1/400

18
Q

how many AA carry the trait of SCD?

A

1/12

19
Q

when does the RBC disform its shape?

A

when it releases oxygen

20
Q

when sickle cell Hb block small arteries and capillaries it leads to

A

ischemia

21
Q

how many days does a sickle cell last?

A

8-10 days

22
Q

how many days does a normal RBC last?

A

120 days