Hematology Flashcards
Components of blood in a hematocrit
Red blood cells, white blood cells, platelets, plasma
Hematocrit
red blood cells in blood 45%
Functions of blood
transports oxygen, nutrients, waste
regulates Ph, buffer
protects- prevents blood loss, infection
maintain temperature
Hemoglobin
Protein in red blood cells, carries oxygen
Importance of Iron
component of hemoglobin, this helps carry oxygen
Life of erythrocytes
120 days
What organs dispose/destroy old erythrocytes.
Spleen
Plasma components
plasma proteins
albumin- osmotic pressure
globulins- attack foreign proteins and pathogens
fibrinogen- assists in blood clotting
lipoproteins- transport cholesterol to cells
83% water
1% other solutes (electrolytes)
Formed elements of blood
Red blood cells (45%)
White blood cells
Platelets
Plasma(45%-65%)
Types of Leukocytes
Never let monkeys eat bananas
Neutrophil, leukocyte, monocyte, eosinophil, basophil (most to least abundant)
Platelets
Thrombocytes, Adhere to damaged site forming plug,
What is hemostasis?
A. vascular spasms- constricts damaged blood vessel, seratonin enhances this
B. Platelet plug information- sticks to damaged endothelium and collagen, prostacyclin
C. COagulation- calcium dependent, prothrombin activator formed then converted to prothrombin into thrombin, thrombin catalyzes joining of fibrinogen molecules- mesh
basophils
0.5% of WBC’s, histamine granules, 2-3 lobed, in connective tissues
eosinophils
1-4% of leukocytes, 2 lobed, red granules, increased in allergic and parasitic responses
monocytes
largest WBC, gray blue cytoplasm, kidney shaped nucleus, go into macrophages
macrophage
Found in WBC, especially at sites of infection
lymphocytes
in lymph tissues, T cells act against infection cells + tumor cells, B cells help to produce antibodies, increased in infections
plasma
non-living fluid matrix, has fagl (fibrinogen- helps with clotts, albumin- osmotic pressure, flobulins- attacks foreign proteins, lipoproteins- transport cholesterol)
hematopoiesis
red blood cells made in red bone marrow, life span of 100-120 days, removed by spleen, liver macrophages destroy, degraded to bilirubin
red bone marrow
where red blood cells are made
phagocytosis
ingestion of bacteria by phagocytes and protozoans, eliminating foreign substances
neutrophils
cytoplasm stains pale lilac, 3-6 lobed nucleus, increased in
bacterial infection
plasma proteins
fagl (fibrinogen- assists in blood clot, albumin- osmotic pressure, globulins- attack foreign proteins, lipoproteins- transport cholesterol)
embolus
moving thrombus, coumadin (prevents blood clots)