Hematology Flashcards

1
Q

Components of blood in a hematocrit

A

Red blood cells, white blood cells, platelets, plasma

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2
Q

Hematocrit

A

red blood cells in blood 45%

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3
Q

Functions of blood

A

transports oxygen, nutrients, waste
regulates Ph, buffer
protects- prevents blood loss, infection
maintain temperature

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4
Q

Hemoglobin

A

Protein in red blood cells, carries oxygen

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5
Q

Importance of Iron

A

component of hemoglobin, this helps carry oxygen

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6
Q

Life of erythrocytes

A

120 days

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7
Q

What organs dispose/destroy old erythrocytes.

A

Spleen

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8
Q

Plasma components

A

plasma proteins
albumin- osmotic pressure
globulins- attack foreign proteins and pathogens
fibrinogen- assists in blood clotting
lipoproteins- transport cholesterol to cells
83% water
1% other solutes (electrolytes)

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9
Q

Formed elements of blood

A

Red blood cells (45%)
White blood cells
Platelets
Plasma(45%-65%)

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10
Q

Types of Leukocytes

A

Never let monkeys eat bananas
Neutrophil, leukocyte, monocyte, eosinophil, basophil (most to least abundant)

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11
Q

Platelets

A

Thrombocytes, Adhere to damaged site forming plug,

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12
Q

What is hemostasis?

A

A. vascular spasms- constricts damaged blood vessel, seratonin enhances this
B. Platelet plug information- sticks to damaged endothelium and collagen, prostacyclin
C. COagulation- calcium dependent, prothrombin activator formed then converted to prothrombin into thrombin, thrombin catalyzes joining of fibrinogen molecules- mesh

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13
Q

basophils

A

0.5% of WBC’s, histamine granules, 2-3 lobed, in connective tissues

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14
Q

eosinophils

A

1-4% of leukocytes, 2 lobed, red granules, increased in allergic and parasitic responses

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15
Q

monocytes

A

largest WBC, gray blue cytoplasm, kidney shaped nucleus, go into macrophages

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16
Q

macrophage

A

Found in WBC, especially at sites of infection

17
Q

lymphocytes

A

in lymph tissues, T cells act against infection cells + tumor cells, B cells help to produce antibodies, increased in infections

18
Q

plasma

A

non-living fluid matrix, has fagl (fibrinogen- helps with clotts, albumin- osmotic pressure, flobulins- attacks foreign proteins, lipoproteins- transport cholesterol)

19
Q

hematopoiesis

A

red blood cells made in red bone marrow, life span of 100-120 days, removed by spleen, liver macrophages destroy, degraded to bilirubin

20
Q

red bone marrow

A

where red blood cells are made

21
Q

phagocytosis

A

ingestion of bacteria by phagocytes and protozoans, eliminating foreign substances

22
Q

neutrophils

A

cytoplasm stains pale lilac, 3-6 lobed nucleus, increased in
bacterial infection

23
Q

plasma proteins

A

fagl (fibrinogen- assists in blood clot, albumin- osmotic pressure, globulins- attack foreign proteins, lipoproteins- transport cholesterol)

24
Q

embolus

A

moving thrombus, coumadin (prevents blood clots)

25
thrombocytes
blood clotting proteins
26
leukocytes
27
fibrinogen
Protein produced in liver that helps clotting
28
hemostasis
blood clotting, vascular spasms, platelets stick to collagen and damaged andotheleum, then calcium dependent reaction, prothrombin activator made and converts prothrombin into thrombin
29
Where are red blood cells made?
Red bone marrow
30
Where are white blood cells made?
Bone marrow
31
Red blood cells are destroyed in....
Spleen