Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PMLS MIDTERMS > Hematology > Flashcards

Hematology Flashcards

1
Q

“Father of Hematology”

A

William Hewson (1770-1773)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

He discovered the role of bone marrow in
HEMATOPOIESIS.

A

FECN
Franz Ernst Christian Neumann (1868)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

developed the WRIGHT STAIN and the refinements

A

James Homer Wright (1902)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

-refinements
-foundation of blood cell identification.

A

Wright’s Romanowsky-type stain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

first to perform a BLOOD COUNT in 1852.

A

Karl Vierordt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

method of karl verordt

A

drawing blood into a capillary tube
spreading collected blood onto a slide
microscopic analysis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

provided an RBC count without the need for manual counting of individual cells.

A

George Oliver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

method of george oliver was based on

A

visual measurement of light loss by scattering and absorption in a test tube filled with diluted blood.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Utilized a PHOTODETECTOR for the measurement of light absorption instead of relying on unaided eyes.

A

Mercandier et al

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Developed cell counting by IMPEDANCE MEASUREMENT.

A

Wallace Coulter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

This method was based on the fact that cells are poor electrical conductors and that they manifest electrical resistance as they pass through a small aperture.

A

impedance measurement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

blood components

A

plasma and platelets
buffy coat/white blood cells
erythrocytes/red blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

percentage of plasma

A

55

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

percentage of buffy coat

A

<1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

percentage of erythrocytes

A

45

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

preparation of plasma

A

NOT allowed to clot prior to separation from cells

used for collection is anticoagulated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

preparation of serum

A

allowed to clot before separation from the clot

used for collection is NOT anticoagulated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

plasma appearance after separation

A

Pale yellow fluid separated from the blood cells via centrifugation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

serum Appearance after
separation

A

Yellow fluid separated from the blood clot via centrifugation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

plasma clotting factor

A

Presence of fibrinogen (Factor I)
Presence of all clotting factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

serum clotting factor

A

Absence of fibrinogen (Factor I)
Absence of Factor V, VIII, XIII, II

22
Q

components of plasma

A

-mostly water
-proteins (albumin)
-electrolytes
-dissolved gases (o2, co2)

23
Q

components of buffy coat

A

platelets
leukocytes
monocytes
lymphocytes
eosinophil
basophil
neutrophil

24
Q

biconcave disc-shaped cells that are anucleated

A

red blood cells

25
Q

pigment that gives whole blood its red color

A

hemoglobin (oxygen-carrying)

26
Q

responsible for physiological gas exchange,
specifically transporting oxygen from the lungs

A

rbc

27
Q

White Blood Cell granulocytes

A

neutrophils
eosinophils
basophils

28
Q

White Blood Cells: agranculocytes

A

monocytes
lymphocytes

29
Q
  • Nucleus has 2-5 lobes
  • Cytoplasm has fine, pale lilac granules with NEUTRAL affinity for
    stains
  • Phagocytic; respond to bacterial infection
  • 50-70% of total WBC population
A

Neutrophils

30
Q
  • Nucleus usually has 2 lobes connected by thick chromatin strand
  • Cytoplasm contains large, red-orange granules with affinity for ACIDIC
  • Responds to parasitic & helminthic infection and allergy
  • Also characterized to have phagocytic activity
  • Comprises 1-3% of the total WBC population
A

Eosinophils

31
Q
  • Nucleus has 2 lobes; often covered by large granules
  • Cytoplasm contains water soluble blue-black granules with affinity for BASIC stains
  • Involved in allergic and hypersensitivity reactions
  • 0-2% of total WBC population
A

Basophils

32
Q
  • Nucleus is HORSESHOE or KIDNEY-SHAPED often with brain-like convolutions
  • Cytoplasm is BLUE-GRAY colored and foamy and has very fine azurophilic granules responsible for the characteristic “GROUND GLASS” appearance
  • converted to macrophages
  • Macrophages are potent phagocytes which defend the body against Mycobacterium species and other bacteria, fungi, protozoa, and viruses
  • 2-11% of total WBC population
A

Monocyte

33
Q
  • ROUND OR SLIGHTLY IDENTIFIEC NUCLES that occupies majority of the
    cell area
  • Scanty cytoplasm with a characteristic “ROBIN’ EGG BLUE COLORATION”
  • IMMUNOCYTES
  • Predominant WBC that responds to several viral infections
  • 18-42% of total WBC population
A

lymphocyte

34
Q

cell fragments that play significant roles in
HEMOSTASIS.

contain many vesicles but have no nucleus.

clump together and form clots to stop bleeding

A

Platelets

35
Q

commonly performed blood test that is often included as part of a routine checkup.

A

Complete Blood Count or CBC

36
Q

CBC can be used to

A

help in the detection of a variety of disorders including
infections, anemia, diseases of the immune system, and blood cancers.

37
Q

primarily used for the diagnosis of anemia

A

Hemoglobin determination

38
Q

condition in which the number of red blood cells or their oxygen-carrying pigment hemoglobin is insufficient to meet physiologic needs.

A

anemia

39
Q

hemoglobin level in women

A

less than 12.0 g/dL

40
Q

hemoglobin level in men

A

less than 13.0 d/dL

41
Q

It is also known as Packed Cell Volume (PCV) or Erythrocyte Volume Fraction (EVF), is the volume percentage of RBCs in a whole blood sample.

A

Hematocrit determination

42
Q

count is often seen in infections, allergy, and leukemic states.

A

Leukocytosis/ High WBC

43
Q

observed in cases of viral infections that temporarily disrupt bone marrow, autoimmune disorders, and immunodeficiency.

A

Leukopenia/ Low WBC count,

44
Q

It is the quantification of thrombocytes of the blood samples.

A

Platelet Count

45
Q

routine procedure that involves observing a total of 100
WBCs and simultaneously classifying them as either neutrophils, lymphocytes, monocytes, eosinophils, and basophils.

A

WBC Differential Count

46
Q

increased in bacterial infection

A

neutrophil

47
Q

increased in viral enfections

A

lmyphocytes

48
Q

increased in TB, syphilis, malignancies

A

monocytes

49
Q

increased in allergies, pasties

A

Eosinophil

50
Q

incrased in immediate hypersensitivity

A

basophil

51
Q

It involves microscopic observation of the size and shape of the red blood cell population of the sample.

A

RBC morphology examination

52
Q

It aids in morphological classification of anemia. MCV, MCH, and MCHC are commonly reported indices.

A

RBC indices

PMLS MIDTERMS (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions