Blood bank Flashcards

1
Q

branch of immunology
use of immunologic principles to study and identify the different blood groups.

A

Immunohematology

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2
Q

collects blood products from donors
preparation and storing whole blood and blood components
for transfusion.

A

Blood bank

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3
Q

he received blood by drinking blood from three young boys.

A

Pope Innocent VII (1492)

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4
Q

He performed the first animal-to-human transfusion by
bloodletting a 16-year-old boy. He exchanged___ of boy’s blood to ___ of lamb’s blood.

A

Jean Baptiste Denis (1667)
3 ounces - 9 ounces

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5
Q

who received a calf’s blood and suffered from a transfusion reaction but survived and became well.

A

Anton Mauroy

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6
Q

He transfused sheep’s blood to a student.

A

Richard Lower

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7
Q

Performed the first human-to-human transfusion in 1795 but this was not documented.

A

Philip Syng Physick

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8
Q

performed and published a set of animal
experiments which proved that the donor and the recipient must be of the same species.

A

John Henry Leacock

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9
Q

successfully transfused a woman dying from postpartum hemorrhage with by transfusing blood from the woman’s husband.

A

James Blundell 1825

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10
Q

Observed red cell lysis in the blood of a woman who died after
receiving a transfusion of sheep blood. He also observed that
incompatible transfusion reactions were associated with hemorrhage and congestion of the kidneys, lungs, and liver.

A

Emil Ponfick

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11
Q

Observed that human red cells would lyse when mixed with the sera of other animals. He set the stage for the study of the immunologic basis of blood incompatibility.

A

Leonard Landois

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12
Q

discovered the ABO blood group in __

A

Karl Landsteiner,1901

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13
Q

and explained the serious reactions that occur in humans as a result of incompatible transfusions

A

Karl Landsteiner; ABO blood group

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14
Q

clumping of cells.

A

Agglutination

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15
Q

C was later to be re-named O for the German word ___, meaning ___).

A

“Ohne” “without”

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15
Q

C was later to be re-named O for the German word ___, meaning ___).

A

“Ohne” “without”

16
Q

discovered the fourth less frequent blood group “AB”.

A

Alfred von Descatello and Adriano Sturli, 1902

17
Q

discovery of Rh blood group by

A

Karl Landsteiner and Alex Weiner 1940

18
Q

The units of heredity; Often defined at the molecular level as a DNA sequence and are responsible for expression of a trait

A

Genes

19
Q

One of two or more alternate forms of a gene

A

Allele

20
Q

The set of genes possessed by an individual organism

A

Genotype

21
Q

A physical trait whose expression depends on the inherited genes along with environmental factors

A

Phenotype

22
Q

Also known as forward or cell typing which determines what
antigens are present on the surface of the patient’s red blood
cells. The specimen to be used here is whole blood and
reagents are commercially prepared ANTISERA.

A

DIRECT TYPING: MOST ROUTINE

23
Q

Also known as indirect or serum typing which determines what antibodies are present in the plasma or serum of the patient’s sample. This method utilizes RED CELL SUSPENSION (RCS) as the reagent.

A

REVERSE TYPING

24
Q

method detects the presence or absence of the D antigen on the surface of the red blood cells. It also categorizes individuals as Rh-positive or Rh-negative.

A

Rh BLOOD TYPING:

25
Q

Rh BLOOD TYPING:
sample is ___ and the reagent is commercially prepared ___ which is colorless.

A

whole blood
Anti-D

26
Q

mixed with donor’s red blood cells.

A

Recipient’s serum
RSDC (Recipient serum + Donor cells)

27
Q

This detects if the recipient has antibodies which can destroy the transfused red blood cells from the donor.

A

MAJOR CROSSMATCH:

28
Q

mixed with the recipient’s red blood cells.

A

Donor’s serum

29
Q

This detects if there are antibodies in the donor’s serum that can destroy the patient’s red blood cells.

A

MINOR CROSSMATCH: