Hematologija Flashcards

1
Q

Cut off vrijednost teške trombocitopenije?

A

10-30 * 10^9 l

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2
Q

Imune trombocitopenije?

A

Heparinom inducirana trombocitopenija HIT

Mb. Werlhof (imuna trombocitopenijska purpura)

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3
Q

Neimune trombocitopenije?

A

DIK

TTP (tromboticka trombocitopenijska purpura)

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4
Q

Najčešći uzročnici DIK-a?

A

Opstetricki sindromi (abruptio placentae)

Metastatski malignomi (mucinozni adenokarcinom)

Bakterijska sepsa (stafilokoki, streptokoki, pneumokoki)

Masivne traume (opekotine, ozebline, ozljede glave)

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5
Q

Obilježja DIK-a?

A
Opsežna krvarenja
Akrocijanoza
Tromboza
Pregangrenozne lezije prstiju
Vazospazam krvnih sudova nos i gen
Produžena krvarenja na mjest povrede
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6
Q

Terapija DIK-a?

A

Nadomjesna terapija: SSP i krioprecipitat
Perakutna faza: heparin
Transfuzija trombocita
Etiološki tretman

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7
Q

Nadomjesna terapija DIK-a?

A

SSP 30-50 ml/kg/dan brzinom 2ml/kg/h

Krioprecipitat (1 jedinica krioprecipitata sadrži 20 mg fibrinogena) kod voluminozno preopterećenih osoba

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8
Q

Cilj nadomjesne terapije DIK-a?

A

Nadomjestiti trombocite na vrijednost 50*10^9 l a fibrinogen (50-100) mg/kg

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9
Q

Perakutna faza DIK-a? Th

A

Heparin (50-100) IU/kg/8h

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10
Q

Kada se vrši transfuzija trombocita?

A

Kada im je vrijednost ispod 20*10^9 l

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