Hematologic Illnesses Flashcards

1
Q

Hemolytic Disorder of the Newborn

A

D antigen present as early as 5 wks
Most common: Anti-D, Anti Kell
“Kidd Kells Duffy Dies, Lewis lives”
Liley curve: Measures optical density of AF in cases of isoimmunization 2/2 hemolytic anemia (bili in AF)
Deliver or do IUT if upper zone II or Zone III
Not possible to follow amnios for Parvo, Kell (cause erythroblastic, not hemolytic anemia)

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2
Q

RhoGAM

A

300mcg dose protects against 30mL fetal blood or 15mL of fetal RBCs

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3
Q

Risks of RhD isoimmunization

A

Term NSVD without rhogam 20%
Rhogam at delivery only 2%
Rhogam at 28wk and PP 0.2% risk

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4
Q

Apt Test

A

Ddx fetal blood from maternal blood in eval of bloody stools

Add base, fetal cells remain pink, adult cells lyse

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