Hematologic Disorders

Question 1

Genetic disorder with abnormally shaped red blood cells.

Answer 1

Sickle Cell Anemia

Hydroxyurea – increases fetal hemoglobin

Folic acid – support RBC production

Opioids/NSAIDs – pain crisis

Penicillin prophylaxis – infection prevention Collaborative:

Hematology team

Pain and fever monitoring

Genetic counseling

Question 2

Inherited bleeding disorder due to clotting factor deficiency.

Answer 2

Hemophilia

Factor VIII or IX concentrates

Desmopressin (DDAVP) – for mild hemophilia A Collaborative:

Hematologist

Avoid IM injections/invasive procedures

Family teaching on bleed precautions

Question 3

Inherited disorder causing reduced hemoglobin production.

Answer 3

Thalassemia

Regular blood transfusions

Deferoxamine / Deferasirox – iron chelation therapy Collaborative:

Hematology

Genetic counseling

Monitor iron overload, liver/heart