hematemesis Flashcards
What lies anterior to the surface of the stomach?
left lateral segment of the liver
What attaches the stomach to the transverse colon?
gastrocolic omentum
What does the gastro-hepatic ligament attach?
the lesser omentum attaches the lesser curvature to the liver
after subtotal gastrectomy where the right & left gastric arteries & the right & left gstro-epiploic arteries are ligated, what supplies the rest of the stomach?
short gastric arteries
What is the main stimulus for gastrin secretion?
meals -> gastric distention
stimulates secretion of HCL
pH <3 inhibits its secretion, alkaline environment stimulates its secretion
somatostatin inhibits it
What should u ask in history taking of a patient presenting with hematemesis with suspected gastric cancer?
- weight loss
- decreased food intake
- anorexia
- early satiety
- abdominal pain
- nausea & vomiting
- bloating
- dysphagia
What will be found on physical examination of patient that has suspected gastric cancer?
- chronic occult blood loss
- Virchow’s node (left supraclavicular)
- abdominal mass
- Krukenberg’s tumor of the ovary
- Sister Joseph’s nodule (umbilical mass in subcutaneous tissue)
- malignant ascites
- Blumer shelf (pouch of douglas)
- Trousseau’s syndrome (thrombophlebitis)
- Acanthosis nigricans
- peripheral neuropathy
- cachexia
What is the first step that should be preformed in order to diagnose the cause of hematemesis?
1- esophagogastrodudonoscopy + biopsy
if afraid of obstruction you can start with upper abdominal series
2- CT -> to detect metastases
last step before operation -> laparoscopy
What are the 2 modules of investigation that we can use to diagnose & take a biopsy?
EGD
EUS
What are the 3 most common primary malignant gastric neoplasms?
adenocarcinoma 95%
lymphoma 4%
malignant GIST 1%
Hematogenous metastasis to the stomach is more likely to occur from?
Melanoma
Breast
Who is more commonly diagnosed with gastric cancer?
elderly
if young -> diffuse, large, aggressive, poorly differentiated, LINTIS PLASTICA
What is the pathogenesis of gastric cancer?
aggregating factor (ex H.pylori) -> chronic superficial gastritis -> atrophic gastritis -> intestinal metaplasia -> dysplasia -> cancer
an E-cadherin gene is associated with?
LINTIS PLASTICA
(diffuse gastric cancer)
consider prophylactic total gastrectomy
Menetrier disease is a risk factor for?
adenocarcinoma