HEMA QUIZ 5 Flashcards by Edcel Grace Cobrilla

What are the initial lab tests for the diagnosis of anemia?

A. Hemogram, reticulocyte count, and differential count
B. Hemogram, and peripheral blood smear
C. Hemogram, peripheral blood smear, and reticulocyte count
D. RBC count, Hematocrit value, & hemoglobin level

C. Hemogram, peripheral blood smear, and reticulocyte count

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Which of the following anemia is NOT associated with impaired hemoglobin synthesis?

A. IDA
B. ACI
C. Sideroblastic anemia
D. Hemolytic anemia

D. Hemolytic anemia

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Refers to a decrease in the number of erythroid precursors in the bone marrow that results in decreased RBC production and anemia

A. Anemia
B. Ineffective erythropoiesis
C. Insufficient erythropoiesis
D. Impaired erythropoiesis

C. Insufficient erythropoiesis

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What is the level of hemoglobin in a patient with severe anemia?

A. Less than 5 mg/dl
B. Less than 7 mg/dl
C. Less than 10 mg/dl
D. Less than 14mg/dl

B. Less than 7 mg/dl

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Which of the following is NOT TRUE regarding to megaloblastic anemia?

A. Erythroleukemia is a megaloblastic anemia
B. MCV usually reach 150 femtoliters
C. Macrocytes are usually round
D. Presence of hypersegmentation

C. Macrocytes are usually round

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Which of the mechanism causes megaloblastic anemia?

A. Impaired hemoglobin synthesis
B. Delay and slower nuclear maturation
C. Delay and slower cytoplasmic maturation
D. Structural defect in the globin chains

B. Delay and slower nuclear maturation

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Increased measurements of homocysteine and methylmalonic acid can aid in the diagnosis of:

A. Iron deficiency
B. Vitamin B12 deficiency
C. Folic acid deficiency
D. Hepcidin level

B. Vitamin B12 deficiency

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Which of the following does not correlate with Non megaloblastic anemia?

A. MCV does not usually exceeds 115 femtoliters
B. May be associated with chronic alcohol ingestion
C. Related to disruption of fats in the cell membrane
D. Presence of hypersegmented WBCs

D. Presence of hypersegmented WBCs

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Patients with rheumatoid arthritis and SLE maybe associated with what type of anemia?

A. IDA
B. Sideroblastic anemia
C. Megaloblastic anemia
D. ACD

D. ACD

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Which of the following lab result does not support the diagnosis of a patient with anemia of chronic inflammation?

A. Increased serum ferritin
B. Increased FEP
C. Normal soluble transferrin receptors
D. Increased % transferrin saturation

D. Increased % transferrin saturation

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In the Thomas plot, which of the following quadrant is associated with latent iron deficiency ?

A. Upper right
B. Lower right
C. Upper left
D. Lower left

A. Upper right

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What is the EPO level in patient with Fanconi’s anemia?

A. Decreased
B. Increased
C. Normal

B. Increased

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An empty bone marrow with pancytopenia is a clinical lab finding of what type of condition?

A. Dyskeratosis congenita
B. Myelopthisic anemia
C. Hemolytic anemia
D. Megaloblastic anemia

A. Dyskeratosis congenita

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Majority of the cases of aplastic anemia are:

A. Inherited
B. Drug induced
C. Idiopathic
D. Secondary to infections

C. Idiopathic

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Which of the following is not a manifestation of Fanconi’s anemia?

A. Short stature
B. Pica
C. Infertility
D. Mental retardation

B. Pica

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What is the WBC count in a patient with Diamond black fan anemia?

A. Increased
B. Decreased
C. Normal

C. Normal

A Bone marrow replacement anemia with increase immature cells in the blood:

A. Hemolytic anemia
B. Aplastic anemia
C. Myelophthisic anemia
D. Diamond black fan anemia

C. Myelophthisic anemia

The earliest hematological change in acute blood loss is a transient decrease of what type of cell/s?

A. RBC
B. WBC
C. Platelets
D. RBC and WBC

C. Platelets

Blood loss anemia that is due to unexpected accident:

A. Chronic type
B. Acute type
C. Sub-acute type
D. Compensatory type

B. Acute type

Which of the following are classifications of hemolytic anemias?

I. Extravascular hemolysis vs intravascular hemolysis
II. Intrinsic defect vs extrinsic defect
III. Immediate vs delayed

A. 1,2
B. 1,2,3
C. 1 and 3
D. 2 and 3

A. 1,2

Which laboratory finding does not correlate with hemolytic anemia?

A. Decrease haptoglobin level
B. Increase serum LD enzyme
C. Decrease reticulocyte count
D. Bilirubinemia

C. Decrease reticulocyte count

A clinical condition with absence of DAF and MIRL in the RBC membrane:

A. PCH
B. PNH
C. WAIHA
D. Aplastic anemia

B. PNH

The auto antibody that is responsible for the hemolysis in a person with PCH belongs to what class?

A. IgG
B. IgM
C. IgA
D. Any of these

A. IgG

Which of the following is not categorized as intravascular hemolysis type of hemolytic anemia?

A. Enzyme defect
B. Hereditary membrane defect
C. Hemoglobinopathies
D. Drug induced

B. Hereditary membrane defect

Which of the following is not example of microangiopathic hemolytic anemia? A. DIC B. TTP C. ITP D. HUS

C. ITP

Which of the following is not related to Hemolytic uremic syndrome? A. An example of hemolytic anemia B. Due to EHEC 0157:H7 C. Renal failure D. Common in elderly people

D. Common in elderly people

Which of the following can be used to differentiate microangiopathic hemolytic anemia form other types of hemolytic anemia? A. Increase haptoglobin levels B. Presence of schistocyte C. Presence of spherocytes D. Reticulocyte is usually normal

B. Presence of schistocyte

What is the most common cause of death in patient with sickle cell disease? A. Aplastic crisis B. Infection C. Hemolysis D. Dehydration

B. Infection

WHICH OF THE FOLLOWING BETATHALASSEMIA IS CHARACTERIZED BY MILD TO MODERATE ANEMIA? A. B-THALASSEMIA MAJOR B. B-THALASSEMIA MINOR C. B-THALASSEMIA INTERMEDIA D. B-THALASSEMIA SILENT CARRIER

C. B-THALASSEMIA INTERMEDIA

A thalassemia can be differentiated from other microcytic anemia due to its presence of: A. defective hemoglobin synthesis B. low MCV result C. codocytes D. hypochromic RBC

C. codocytes

Which of the following hemoglobin move fastest towards the anode in citrate electrophoresis? A. Hb S B. Hb C C. Hb A D. Hb F

B. Hb C

A hemoglobin disorder caused when glycine replaces glutamic acid at position 121 on the beta chain: A. Beta thalassemia B. Hemoglobin D-punjab C. Hemoglobin G D. Hemoglobin E

B. Hemoglobin D-punjab

Structurally abnormal hemoglobins can be seen in which of the following condition? A. Thalassemia B. Hemoglobinopathies C. Hemolytic anemia D. Any of these

B. Hemoglobinopathies

Which of the following type of alpha thalassemia is common in Asia? A. Silent carrier B. Minor or trait C. Major D. Hb H disease

D. Hb H disease

Presence of three alpha genes can be seen in what condition? A. Alpha thalassemia major B. Hb H disease C. Silent carrier alpha thalassemia D. Alpha thalassemia minor

C. Silent carrier alpha thalassemia

A definitive diagnosis of thalassemia requires the patient to undergo: A. Cell counting B. Chemical analysis C. Molecular testing D. Supravital staining

C. Molecular testing

What is the composition of Bart's hemoglobin? A. 4 gamma B. 4 Beta C. 4 alpha D. NOTA

A. 4 gamma

Which of the following hemoglobin migrates slowest towards the anode of alkaline hemoglobin electrophoresis? A. Hemoglobin A B. Hemoglobin C C. Hemoglobin S D. Hemoglobin F

B. Hemoglobin C