HEMA QUIZ 4 Flashcards

1
Q

It is the coefficient of variation of RBC volume expressed as percentage

A. MCHC
B. RDW
C. MCV
D. Relative count

A

B. RDW

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2
Q

What is the fourth RBC index?

A. RDW
B. Reticulocyte production index
C. RBC maturation time
D. MCH

A

A. RDW

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3
Q

Normal RBCs have central pallor that is approximately __ in diameter

A. ½
B. 1/3
C. 2/3

D. ¼

A

B. 1/3

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4
Q

Identify: Regular 10-30 scalloped short projections evenly distributed

A. Acanthocyte
B. Schistocyte
C. Echinocyte
D. Keratocyte

A

C. Echinocyte

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5
Q

RBC with membrane folded over can be seen in what condition?

A. Sickle cell
B. Hb C disease
C. Thalassemia
D. DIC

A

B. Hb C disease

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6
Q

With Blue-berry bagel appearance and formed due to precipitation of RNA:

A. Heinz bodies
B. Basophilic stipplings
C. Punctuate of basophilia
D. Hb H

A

B. Basophilic stipplings

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7
Q

Fine, evenly dispersed, dark blue granules; imparts golf ball appearance to RBCs

A. Heinz bodies
B. Basophilic stipplings
C. Punctuate of basophilia
D. Hb H

A

D. Hb H

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8
Q

Which of the following condition is not associated with Rouleaux formation?

A. Hyperfibrinogenemia
B. Cold agglutinin disease
C. Multiple myeloma
D. NOTA

A

B. Cold agglutinin disease

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9
Q

What is the most common Neubauer counting chamber?

A. Levy
B. Fuchs Rosenthal
C. Petroff-Hausser
D. Jessen

A

A. Levy

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10
Q

What is the total area of each grid in the Neubauer counting chamber?

A. 4mm2
B. 25 mm2
C. 9mm2
D. 16mm2

A

C. 9mm2

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11
Q

The depth or distance between each counting surface and the coverslip in a Neubauer counting chamber is:

A. 1mm
B. 0.1mm
C. 1mm2
D. 0.1 mm2

A

B. 0.1mm

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12
Q

What is the size of each small RBC squares located in the central square of the Neubauer counting chamber?

A. 0.2mm2
B. 0.04 mm2
C. 1mm2
D. 0.5mm2

A

B. 0.04 mm2

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13
Q

What is the best RBC diluting fluid?

A. NSS
B. Formol citrate
C. Gower’s fluid
D. Hayem’s fluid

A

B. Formol citrate

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14
Q

Which of the following is not a component of Gower’s fluid?

A. Glacial acetic acid
B. Distilled water
C. Sodium chloride
D. Sodium sulphate

A

C. Sodium chloride

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15
Q

What is the standard WBC dilution factor used for manual counting?

A. 1:20
B. 1:100
C. 1:200
D. 1:10

A

A. 1:20

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16
Q

WBC counts should be performed within how many hours of dilution?

A. 1 hour
B. 2 hours
C. 3 hours
D. 4 hours

A

C. 3 hours

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17
Q

Which of the following parameter is least likely used to classify anemia according to morphology?

A. MCV
B. MCH
C. MCHC
D. RDW

A

B. MCH

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18
Q

Which of the following parameters are included in the computation of MCHC?

A. Hematocrit, Hemoglobin, RBC count
B. Hematocrit, Hemoglobin
C. Hematocrit, RBC count
D. Hematocrit, Retic count

A

B. Hematocrit, Hemoglobin

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19
Q

How many drops of a 50 ul New-methylene blue should be used for reticulocyte counting?

1-2
2-3
3-4
4-5

A

2-3

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20
Q

Which of the following parameter of an automated hematology test provides an early indication of engraftment success after hematopoietic stem cell transplantation?

A. IRF
B. Reticulocyte Hemoglobin assay
C. RPI
D. Miller disk counting

A

A. IRF

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21
Q

What is the third layer of a spun hematocrit capillary tube?

A. Buffy coat
B. Plasma
C. Packed RBCs
D. Fatty layer

A

A. Buffy coat

22
Q

Which of the following is true regarding hematocrit reading?

A. Automated hematocrit results maybe higher by 1-3% compared to manual microhematocrit method
B. Automated hematocrit result maybe lower by 1-3% compared to manual microhematocrit method
C. Automated hematocrit result is always the same compared to manual microhematocrit method

A

B. Automated hematocrit result maybe lower by 1-3% compared to manual microhematocrit method

23
Q

The value of duplicate hematocrit results should agree within how many percent?

1%
2%
3%
5%

A

1%

24
Q

Delay in the reading of microhematocrit test will affect the results in what way?

A. Lead to false increase results
B. Lead to false decrease results
C. It will not affect the results
D. Results may vary

A

A. Lead to false increase results

25
Q

Introduction interstitial fluid and causes _______ hematocrit results.

A. Falsely elevated
B. Falsely lower
C. Will not affect results

A

B. Falsely lower

26
Q

After an acute blood loss, hematocrit results maybe __

A. Higher
B. Lower
C. May Remain as normal

A

B. Lower

27
Q

What type of specimen will the rule of three be applicable?

A. Normocytic, Normochromic
B. Macrocytic, Normochromic
C. Microcytic, Microcytic
D. Macrocytic, Spherocytic

A

A. Normocytic, Normochromic

28
Q

Which of the following is not true about rule of three for computing hematocrit results?

A. It is used for checking validity of test results
B. A patient with 10g/dl of hemoglobin will have a 27-33% hematocrit result
C. Applicable for sample patient with Iron deficiency anemia
D. NOTA

A

C. Applicable for sample patient with Iron deficiency anemia

29
Q

Which of the following is the most commonly used method for ESR testing?

A. Westergren
B. Modified westergren
C. Wintrobe
D. Landsberg

A

B. Modified westergren

30
Q

Which of the following should not be done in ESR testing?

A. Placing the ESR tube in a 90-degree angle
B. Placing the ESR tube on top of the refrigerator
C. Waiting the result for an hour
D. Using Citrate as an anticoagulant

A

B. Placing the ESR tube on top of the refrigerator

31
Q

Which of the following is associated with decreased ESR value?

A. Leukemia
B. Salicylate ingestion
C. Heparin administration
D. Refrigerated sample not returned to room temperature

A

B. Salicylate ingestion

32
Q

Osmotic fragility test is an old confirmatory test for what condition?

A. IDA
B. Hereditary spherocytosis
C. Sickle cell
D. Unstable hemoglobins

A

B. Hereditary spherocytosis

33
Q

Which of the following anticoagulant can be used for OFT?

A. EDTA
B. Heparin
C. Citrate
D. Oxalate

A

B. Heparin

34
Q

In OFT, a normal complete hemolysis should be observed at what tube number?

A. Tuber 20
B. Tube 18
C. Tube 17
D. Tube 15

A

C. Tube 17

35
Q

What is the reagent used to lyse the RBC in the solubility test for HB S?

A. Sodium hydrosulfite
B. Sodium dithionite
C. Saponin
D. Reducing agent

A

C. Saponin

36
Q

Which of the following will give a positive result in solubility test for Hb S?

A. Infants
B. Patient with abnormally low hematocrit
C. Hb C
D. Absence of turbidity

A

C. Hb C

37
Q

he acid elution test is used for the detection of:

A. Hemoglobin A
B. Hemoglobin S
C. Hemoglobin F
D. Unstable hemoglobin

A

C. Hemoglobin F

38
Q

Which of the following serves as the counterstain in Kleihauer-Betke stain?

A. Acid hematoxylin
B. Safranin
C. Eosin
D. Carbolfuchsin

A

C. Eosin

39
Q

In heat precipitation test, a normal hemoglobin will:

A. Will not precipitate
B. Will produce precipitate
C. Will produce a red hemolysate
D. Will precipitate and produces a red hemolysate

A

A. Will not precipitate

40
Q

What is the specimen used for sugar water screening and sucrose hemolysis test?

A. Citrated blood
B. EDTA- whole blood
C. Heparinized blood
D. Defibrinated blood

A

A. Citrated blood

41
Q

Eosin Maleimide is a new technique for the diagnosis of hereditary spherocytosis that is based on what principle?

A. Flow cytometry
B. Spectrophotometry
C. Solubility
D. Precipitation

A

A. Flow cytometry

42
Q

he difference between the total cells counted on each side should be __

<5%
<10%
<20%
<15%

A

<10%

43
Q

Inclusion that represents nuclear remnants or abnormal histone biosynthesis:

A. Heinz
B. Cabot rings
C. Pappenheimer
D. Howell Jolly

A

B. Cabot rings

44
Q

RBC diluting fluids are usually:

A. Isotonic
B. Hypotonic
C. Hypertonic
D. Any of these

A

A. Isotonic

45
Q

Charging the hemocytometer requires holding the tube at what angle?

A. 90
B. 45
C. 15
D. 30

A

B. 45

46
Q

Which of the following is false regarding corrected WBC count?

A. Nucleated RBCs are not lysed by WBC diluting fluid
B. At least 5 nRBCs should be present before computing for the correct WBC count
C. Automated WBC results are elevated if nRBCs are present
D. NOTA

A

D. NOTA

47
Q

High RDW results correlates with __ RBC population

A. Uniform
B. Homogenous
C. Heterogenous
D. Equal

A

C. Heterogenous

48
Q

Miller disc can be used for counting of what type of cell?

A. Non-nucleated immature RBC
B. WBC
C. RBC
D. Nucleated RBC

A

A. Non-nucleated immature RBC

49
Q

What is the normal ESR value in children?

10-20 mm/hr
0-5mm/hr
0-10mm/hr
10-15mm/hr

A

0-10mm/hr

50
Q

Which of the following is not a correct way of performing manual microhematocrit method?

A. First drop of blood should be wiped off
B. Buffy coat is included when reading the result
C. Seal the end of the tube with the colored ring using nonabsorbent clay
D. The sealed end of the filled capillary tube should be placed away from the center of the centrifuge

A

B. Buffy coat is included when reading the result