HEMA-IMMUNO CASE 1 & 2 Flashcards
MALT lymphoma of the skin may be related to which of the following?
a. Chlamydophilia psittaci
b. Campylobacter jejuni
c. Borrelia burgdoferi
d. Hepatitis C virus
C.
Chlamydophilia psittaci - eyes/conjunctiva
Campylobacter jejuni - intestines
The following are associated with EBV infection, except:
a. Primary CNS diffuse large B-cell lymphoma
b. Adult T-cell Leukemia
c. Burkitt’s lymphoma
d. Extranodal NK/T-cell lymphoma, nasal type
B.
It is most common in children and mostly associated with immunosuppression and autoimmune diseases
a. Burkitt’s lymphoma
b. DLBCL
c. Follicular lymphoma
d. Lymphoblastic lymphoma
B.
Most common translocation is t(2:5)
a. AITL
b. MCL
c. MALT
d. ALCL
D.
Which of the following is true about Hodgkin lymphoma?
a. More frequent involvement of multiple peripheral nodes
b. Noncontiguous spread
c. Orderly spread by contiguity
d. Extranodal presentation common
C.
Which of the following is true about diffuse large B-cell lymphoma?
a. Most common form of indolent non-Hodgkin lymphoma in US
b. Strongly associated with chromosomal translocations involving BCL2
c. Hallmark is (14; 18) translocation
d. Relatively large size lymphocytes, diffuse pattern of growth
C.
HTLV-1 infection is associated with which of the following T-cell neoplasms?
a. Peripheral T-cell lymphoma, unspecified
b. Anaplastic large cell lymphoma
c. Adult T-cell leukemia
d. Mycosis fungoides/Sezary syndrome
C.
Which of the following T-cell neoplasms is characterized by presence of rearrangements in ALK gene on chromosome 2p23?
a. Peripheral T-cell lymphoma, unspecified
b. Anaplastic large cell lymphoma
c. Adult T-cell leukemia
d. Mycosis fungoides/Sezary syndrome
B.
It is the leading cause of SVCS
a. malignant lymphoma
b. aortic aneurysm
c. thrombosis
d. fibrosing mediastinitis
A.
Most significant chest radiographic finding of SVCS
a. pleural effusion
b. widening of the superior mediastinum
c. oppacities
B.
It is a potentially life-threatening complication of SCVS
a. upper airway obstruction
b. pulmonary edema
c. heart failure
d. tracheal obstruction
D.
Primary treatment for SVCS
a. radiation therapy
b. chemotherapy
c. endovascular therapy
d. stenting
A.
It is accurate for staging to assess lympadenopathy for indolent lymphomas
a. CT scan
b. PET scan
c. MRI
d. FDG-PET
A.
FDG-PET - aggressive dse
It is sensitive for detecting both nodal and extranodal sites involved by NHL
a. CT scan
b. PET scan
c. MRI
d. FDG-PET
D.
It is useful in detecting bone, bone marrow, and CNS dse in the brain and spinal cord
a. CT scan
b. PET scan
c. MRI
d. FDG-PET
C.
The following are clinical risk factors, except:
a. age >60 years old
b. <70 Karnofsky
c. <1 site of extranodal involvement
d. serum lactate dehydrogenase levels elevated
C.
A 65year old male, wheelchair-borne presents with fever, he also complained of night sweats, upon history taking, he was noted to have weight loss and is only capable of limited self care, and laboratory examinations revealed elevated LDH. What is patient’s ECOG score?
a. 1
b. 2
c. 3
d. 4
D.
A 65year old male, wheelchair-borne presents with fever, he also complained of night sweats, upon history taking, he was noted to have weight loss and is only capable of limited self care, and laboratory examinations revealed elevated LDH. He previously undergone chemotherapy with R-CHOP. What is the patient’s prognosis?
a. good
b. intermediate
c. poor
C.
Form of Burkitt’s lymphoma that presents as a jaw tumor and are EBV-positive
a. endemic
b. nonendemic
c. immunodeficiency-related
A.
The following statements are true about Burkitt’s lymphoma, except:
a. BL has a male predominance
b. positive for B-cell antigens CD19 and CD20
c. tumor consists of proliferation of large, atypical lymphocytes giving rise to classic “starry sky” appearance
d. majority of nonendemic BLs are EBV negative
C.
It is the standard first line of therapy for DLBCL
a. Rituximab, Cyclophosphamide, Dacarbazine, Vincristine, Prednisone
b. Rituximab, Cyclophosphamide, Dacarbazine, Vinblastin, Prednisone
c. Rituximab, Cyclophosphamide, Doxorubicin, Vinblastin, Prednisone
d. Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone
D.
WHO classification of Follicular lymphoma that is aggressive and is most similar to DLBCL
a. Grade IIa
b. Grade II
c. Grade III
d. Grade IIIb
D.
The following are true about anaplastic large-cell lymphoma
a. disease of older individuals
b. most closely resembles CD4+ follicular helper T cells
c. localized within the lymph node sinuses
d. pathognomonic malignant “flower cell”
C.
Treatment for patient with advanced stage Hodgkin’s Lymphoma
a. R-CHOP
b. radiotherapy
c. ABVD
d. EPOCH-R
C.
