HEMA

Question 1

Anticoagulant of choice for platelet coagulation studies

Answer 1

Citrate

Question 2

A structure found in WBCs that can be used to determine the sex of an individual?

Answer 2

Barr body

Question 3

All of the statements are true regarding platelets except:

Answer 3

It came from the MEGAKARYOCYTE NUCLEUS

Question 4

The APTT reagent consists of two components which are:

Answer 4

Platelet substitute and an activator

Question 5

The smallest leukocyte is:

Answer 5

Lymphocyte

Question 6

Another name for juveniles

Answer 6

Metamyelocyte

Question 7

Diluent for WBC count

Answer 7

None

Question 8

1 % ammonium oxalate in distilled water is a type of diluent for what type of a cell count

Answer 8

Platelet

Question 9

All of the following are consistent with leukemoid reaction except:

Answer 9

Auer rods - AML

Question 10

Which of these EDTA concentrations is recommended for complete anticoagulation without cellular alteration

Answer 10

1.5 mg/dL

Question 11

High molecular weight kininogen is also known as:

Answer 11

Fitzgerald factor

Question 12

The activated partial thromboplastin time (APTT) is used as a screen for the laboratory evaluation of inherited or acquired deficiencies in the:

Answer 12

Intrinsic pathway of coagulation cascade

Question 13

Based on the following data, what is the most likely factor deficiency?

PT​​​​ Normal
APTT​​​​ Prolonged
APTT + normal plasma​​ Correction
APTT + adsorbed plasma​​ No correction
APTT + aged serum​​ Correction

Answer 13

Factor IX

Question 14

Calculate the WBC count if blood is drawn to the 1.0 mark in a WBC diluting pipette and a total of 150 WBCs are counted in 4 large squares?

Answer 14

3.75x10^9?L

Question 15

A 50-year-old woman who has been receiving bulsufan for 3 years for chronic myelogenous leukemia becomes anemic. Laboratory tests reveal

Answer 15

Acute lymphocytic anemia

Question 16

The recommended type of microscopy for the performance of manual platelet count is?

Answer 16

Phase contrast

Question 17

To evaluate normal platelet numbers in an appropriate area of a blood smear, approximately how many platelets, should be observed per oil immersion field?

Answer 17

8-20

Question 18

A patient has a history of mild hemorrhagic episodes. Laboratory results include a prolonged prothrombin time and activated partial thromboplastin time. The abnormal prothrombin time was corrected by normal and adsorbed plasma, but not aged serum. Which of the following coagulation factors is deficient?

Answer 18

Factor V

Question 19

The abnormal APTT seen in pathological circulating anticoagulant is:

Answer 19

Not corrected with any of the above

Question 20

Which of the following laboratory resukts would be seen in a patient with acute disseminated intravascular coagulation (DIC)?

Answer 20

Prolonged PT, Decreased fibrinogen, decreased platelet count, increased FDP

Question 21

The Philadelphia chromosome is associated with

Answer 21

Chronic granulocytic anemia

Question 22

A normal bleeding time by the Ivy method falls in what range?

Answer 22

1-6 minutes

Question 23

Parahemophilia is due to a deficiency of factor

Answer 23

V

Question 24

Type of Pelger Huet Anomaly usually seen at what state?

Answer 24

Dominant

Question 25

Describes the morphology of Pelger Huet Anomaly

Answer 25

Pince nez appearance

Question 26

Deficiency of sphingomyelinase in MACs

Answer 26

Neilmann Pick disease

Question 27

First factor affected by Coumarin

Answer 27

VII

Question 28

Factor affected when plasma is stored

Answer 28

VIII

Question 29

Describes a well made blood fil

Answer 29

Gradual transition from thick to thin

Question 30

Identify ANLL type: >30% of non-erythroid cells. 50% erythrocytes

Answer 30

M6

Question 31

Which of the following is contained in the primary granules of the neutrophil?

Answer 31

Myeloperoxidase

Question 32

Disseminated intravascular coagulation (DIC) is most often associated with which of the following types of acute leukemia?

Answer 32

Acute promyelocytic leukemia

Question 33

In essential thrombocythemia, the platelets are:

Answer 33

Increased in number and functionally abnormal

Question 34

Which of the following initiates in vivo coagulation by activation of factor VII?

Answer 34

Tissue factor

Question 35

Aspirin prevents platelet aggregation by inhibiting the action of which enzyme?

Answer 35

Cyclo-oxygenase

Question 36

Which of the following is associated with multiple factor deficiencies?

Answer 36

Severe liver disease

Question 37

Which statement regarding protein C is correct?

Answer 37

Its activity is enhanced by Protein S

Question 38

A Miller disk is an ocular device used to facilitate counting of:

Answer 38

Reticulocytes

Question 39

What is the normal value of MCH?

Answer 39

27-32

Question 40

Abnormal Cells seen in Hodgkin’s lymphoma.

Answer 40

Reed-Sternberg cells

Question 41

Stage in megakaryocytic series where thrombocytes are already visible.

Answer 41

Metamegakaryocyte

Question 42

Coagulation Factors that are member of the contact group.

Answer 42

AOTA

Question 43

Coagulation factors that are member of the prothrombin group.

Answer 43

AOTA

Question 44

WBC anomaly that is characterized as having ineffective phagocytosis and recurrent fungal infection?

Answer 44

Chediak-Higashi Granules

Question 45

Which of the following if deficient would cause clinically significant bleeding?

Answer 45

Prothrombin

Question 46

Which of the following has multiple autocatalytic functions and is considered as the key protease of the coagulation pathway?

Answer 46

Thrombin

Question 47

What is the color of the vacuum tube stopper that is used for blood collection for PCR?

Answer 47

White

Question 48

The Philadelphia chromosome

Answer 48

Translocation between longarm 9 and 22

Question 49

Which is a character of an ideal blood film. ​I – The film is 2/3 to ¾ the length of slide. ​II - The film formed a bullet shape. ​III – The feather edge contain a rainbow edge. ​IV - The films contains holes on sides.

Answer 49

I and III

Question 50

Most common leukemia found in children

Answer 50

Acute lymphocytic