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HEMA Flashcards

1
Q

Anticoagulant of choice for platelet coagulation studies

A

Citrate

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2
Q

A structure found in WBCs that can be used to determine the sex of an individual?

A

Barr body

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3
Q

All of the statements are true regarding platelets except:

A

It came from the MEGAKARYOCYTE NUCLEUS

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4
Q

The APTT reagent consists of two components which are:

A

Platelet substitute and an activator

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5
Q

The smallest leukocyte is:

A

Lymphocyte

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6
Q

Another name for juveniles

A

Metamyelocyte

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7
Q

Diluent for WBC count

A

None

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8
Q

1 % ammonium oxalate in distilled water is a type of diluent for what type of a cell count

A

Platelet

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9
Q

All of the following are consistent with leukemoid reaction except:

A

Auer rods - AML

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10
Q

Which of these EDTA concentrations is recommended for complete anticoagulation without cellular alteration

A

1.5 mg/dL

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11
Q

High molecular weight kininogen is also known as:

A

Fitzgerald factor

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12
Q

The activated partial thromboplastin time (APTT) is used as a screen for the laboratory evaluation of inherited or acquired deficiencies in the:

A

Intrinsic pathway of coagulation cascade

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13
Q

Based on the following data, what is the most likely factor deficiency?

PT​​​​ Normal
APTT​​​​ Prolonged
APTT + normal plasma​​ Correction
APTT + adsorbed plasma​​ No correction
APTT + aged serum​​ Correction

A

Factor IX

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14
Q

Calculate the WBC count if blood is drawn to the 1.0 mark in a WBC diluting pipette and a total of 150 WBCs are counted in 4 large squares?

A

3.75x10^9?L

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15
Q

A 50-year-old woman who has been receiving bulsufan for 3 years for chronic myelogenous leukemia becomes anemic. Laboratory tests reveal

A

Acute lymphocytic anemia

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16
Q

The recommended type of microscopy for the performance of manual platelet count is?

A

Phase contrast

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17
Q

To evaluate normal platelet numbers in an appropriate area of a blood smear, approximately how many platelets, should be observed per oil immersion field?

A

8-20

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18
Q

A patient has a history of mild hemorrhagic episodes. Laboratory results include a prolonged prothrombin time and activated partial thromboplastin time. The abnormal prothrombin time was corrected by normal and adsorbed plasma, but not aged serum. Which of the following coagulation factors is deficient?

A

Factor V

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19
Q

The abnormal APTT seen in pathological circulating anticoagulant is:

A

Not corrected with any of the above

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20
Q

Which of the following laboratory resukts would be seen in a patient with acute disseminated intravascular coagulation (DIC)?

A

Prolonged PT, Decreased fibrinogen, decreased platelet count, increased FDP

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21
Q

The Philadelphia chromosome is associated with

A

Chronic granulocytic anemia

22
Q

A normal bleeding time by the Ivy method falls in what range?

A

1-6 minutes

23
Q

Parahemophilia is due to a deficiency of factor

A

V

24
Q

Type of Pelger Huet Anomaly usually seen at what state?

A

Dominant

25
Q

Describes the morphology of Pelger Huet Anomaly

A

Pince nez appearance

26
Q

Deficiency of sphingomyelinase in MACs

A

Neilmann Pick disease

27
Q

First factor affected by Coumarin

A

VII

28
Q

Factor affected when plasma is stored

A

VIII

29
Q

Describes a well made blood fil

A

Gradual transition from thick to thin

30
Q

Identify ANLL type: >30% of non-erythroid cells. 50% erythrocytes

A

M6

31
Q

Which of the following is contained in the primary granules of the neutrophil?

A

Myeloperoxidase

32
Q

Disseminated intravascular coagulation (DIC) is most often associated with which of the following types of acute leukemia?

A

Acute promyelocytic leukemia

33
Q

In essential thrombocythemia, the platelets are:

A

Increased in number and functionally abnormal

34
Q

Which of the following initiates in vivo coagulation by activation of factor VII?

A

Tissue factor

35
Q

Aspirin prevents platelet aggregation by inhibiting the action of which enzyme?

A

Cyclo-oxygenase

36
Q

Which of the following is associated with multiple factor deficiencies?

A

Severe liver disease

37
Q

Which statement regarding protein C is correct?

A

Its activity is enhanced by Protein S

38
Q

A Miller disk is an ocular device used to facilitate counting of:

A

Reticulocytes

39
Q

What is the normal value of MCH?

A

27-32

40
Q

Abnormal Cells seen in Hodgkin’s lymphoma.

A

Reed-Sternberg cells

41
Q

Stage in megakaryocytic series where thrombocytes are already visible.

A

Metamegakaryocyte

42
Q

Coagulation Factors that are member of the contact group.

A

AOTA

43
Q

Coagulation factors that are member of the prothrombin group.

A

AOTA

44
Q

WBC anomaly that is characterized as having ineffective phagocytosis and recurrent fungal infection?

A

Chediak-Higashi Granules

45
Q

Which of the following if deficient would cause clinically significant bleeding?

A

Prothrombin

46
Q

Which of the following has multiple autocatalytic functions and is considered as the key protease of the coagulation pathway?

A

Thrombin

47
Q

What is the color of the vacuum tube stopper that is used for blood collection for PCR?

A

White

48
Q

The Philadelphia chromosome

A

Translocation between longarm 9 and 22

49
Q

Which is a character of an ideal blood film.
​I – The film is 2/3 to ¾ the length of slide.
​II - The film formed a bullet shape.
​III – The feather edge contain a rainbow edge.
​IV - The films contains holes on sides.

A

I and III

50
Q

Most common leukemia found in children

A

Acute lymphocytic

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