helper T cells and how they work

Question 1

two sub classes of helper T cells

Answer 1

Th1 and Th2

Question 2

Th1 recognizes what?

Answer 2

ALL viral, cancer

Question 3

Th2 recognizes what?

Answer 3

ALL bacterial

Question 4

Th1 talks to…?

Answer 4

cytotoxic T cell

Question 5

Th2 talks to…?

Answer 5

B Cells

Question 6

Th1 primary target

Answer 6

intracellular pathogens

Question 7

Th2 primary target

Answer 7

extracellular pathogens

Question 8

Th1 cytokine promoting differentiation by APC

Answer 8

IL-1, IL-2 and others

Question 9

Th2 cytokine promoting differentiation by APC

Answer 9

IL-1, IL-2 and others

Question 10

Th1 cytokine secreted?

Answer 10

IL-2, interferon gamma and others

Question 11

Th2 cytokine secreted?

Answer 11

IL-4, IL-5, and IL-6

Question 12

Th1 cells activated?

Answer 12

macrophages, cytotoxic T cells (T-T cooperation)

Question 13

Th2 cells activated?

Answer 13

B cells into plasma cells (T-B cooperation)

Question 14

Th1 process mediated?

Answer 14

cellular immunity

Question 15

Th2 process mediated?

Answer 15

humoral immunity

Question 16

helper T cell (T4) target?

Answer 16

cytotoxic T cells
B cells
NK cells & macrophages

Question 17

cytotoxic T cell target?

Answer 17

cells with specific antigen bound to class I MHC

Question 18

B cell (10-20% of lymphocytes)

Answer 18

plasma cells release antibodies

Question 19

helper T cell (T4) unique

Answer 19

CD4 protein in membrane binds with MHC class II
activated cells release:
interferon gamma
IL-2
IL-4
IL-5

Question 20

cytotoxic T cell unique

Answer 20

CD8 protein in membrane binds to MHC class I 
produces perforins and releases some stuff

Question 21

B cell unique

Answer 21

immunoglobulin production receptors and production of
IL-1
TNF gamma
MHC class II protein (APC)

Question 22

helper T cell receptors

Answer 22

IL-1
TNF-gamma
IL-6
IL-2+

Question 23

cytotoxic T cell receptors

Answer 23

IL-2+
interferon gamma
antigen bound to MHC class I protein

Question 24

B cell receptors

Answer 24

IL-2
IL-4
IL-5
antigen bound to MHC class II