Heller Ch. 1 Flashcards
CV overview
What 3 conditions does the CV system regulate to control the composition of interstitial fluid?
- Blood flow through capillaries
- The chemical composition of the incoming blood is controlled to be that which is optimal in the interstitial fluid
- Short diffusion distances
What are the major body fluid compartments and what are the volumes in each?
Circulating plasma compartment (3L) Intracellular compartment (30L) Interstitial compartment (12L)
What is the relationship between flow and blood pressure and vascular resistance?
Q = dP/R
What is the relationship of resistance and tube radius?
R is proportional to r^-4
What is the relationship of resistance and fluid viscosity?
R is proportional to viscosity (Ex: anemia decreases viscosity–>decreases resistance to flow)
What causes dramatic increases in heart rate?
Increased blood flow in other areas–dilated blood vessels (exercise, anaphylaxis, etc)
What causes dramatic decreases in heart rate?
Innate heart problem (arrhythmia)
What 5 factors are essential to proper ventricular pumping action?
- Contraction must be regular and synchronized
- Valves must not be stenotic
- Valves must not be insufficient or regurgitant
- Muscle contractions must be forceful
- Ventricles must fill adequately during diastole
What are sympathetic effects on the heart?
Increases heart rate
Increases contractility
What does elastin in arteries allow?
Elastin allows the arteries to stretch during systole and then contract during diastole
Where is blood flow mostly regulated?
Arterioles because of there thick smooth musculature–usually in contracted position
What is the effect of NE (sympathetic) on vasculature via alpha-adrenergic receptors?
NE causes metabolic vasoconstriction (both arteries and veins)
What is the effect of Ach (parasympathetic) on vasculature?
Cholinergic dilation
What is difference between alpha and beta adrenergic receptors?
Alpha is in the vessels
Beta is in the heart
Catecholamine…What is it?
Fancy lingo for epinephrine/norepinephrine