Helicobacter pylori Flashcards
GRAM-NEGATIVE RODS RELATED TO THE ENTERIC TRACT
1
Q
Helicobacter pylori Disease
A
1_Gastritis and peptic ulcer.
2_ Risk factor for gastric carcinoma.
2
Q
Characteristics of h.pylori
A
Curved gram-negative rod.
3
Q
Habitat of H.pylori
A
Habitat is the human stomach.
4
Q
Transmission of H.pylori
A
Transmission is by ingestion
5
Q
Pathogenesis of H.pylori
A
1_Organisms synthesize urease, which produces ammonia that damages gastric mucosa.
2_Ammonia also neutralizes acid pH in stomach, which allows the organism to live in gastric mucosa.
6
Q
Laboratory Diagnosis of H.pylori
A
1_Gram stain and culture.
2_Urease positive.
3Serologic tests for antibody
4“urea breath” test are useful.
7
Q
Treatment of H.pylori
A
1_Amoxicillin
2_metronidazole
3_bismuth (Pepto-Bismol).
8
Q
Prevention
A
No vaccine or drug is available.
