Campylobacter jejuni

Question 1

Campylobacter jejuni disease

Answer 1

Enterocolitis

Question 2

Characteristics of Campylobacter jejuni

Answer 2

1_Comma-shaped gram-negative rods. 2_Microaerophilic. Grows well at 42°C.

Question 3

Habitat of Campylobacter jejuni

Answer 3

Habitat is human and animal feces.

Question 4

Transmission of Campylobacter jejuni

Answer 4

fecal–oral route

Question 5

Pathogenesis of Campylobacter jejuni

Answer 5

1—Invades mucosa of the colon but does not penetrate;
therefore, sepsis rarely occurs.
2_No enterotoxin known.

Question 6

Laboratory Diagnosis of Campylobacter jejuni

Answer 6

1—Gram-stained smear plus culture on special agar (e.g., Skirrow’s agar)
at 42°C in high-CO2,
low-O2 atmosphere. Serologic tests not useful.

Question 7

Treatment of Campylobacter jejuni

Answer 7

1—Usually symptomatic treatment only; 2_erythromycin for severe disease.

Question 8

Prevention of Campylobacter jejuni

Answer 8

1—Public health measures (e.g., sewage disposal, chlorination of the water supply, stool cultures for food handlers, and handwashing prior to food handling).
2_ No preventive vaccine or drug is available.

Question 9

Vaccine of Campylobacter jejuni

Answer 9

No preventive vaccine or drug is available.