HEENT- Adults Flashcards
Conjunctivitis: Most common types
- Viral – often caused by adenovirus
- Allergic – can be seasonal or perennial
- Vernal and atopic –
o Vernal – more common in childhood
o Atopic – adults with hx asthma, allergic rhinitis, eczema - Non allergic – reaction to irritant,
o e.g. contact lenses, artificial smoke - Bacterial – extremely rare in adults
viral conjunctivitis
- Typically caused by adenovirus, many types
- Starts with URI symptoms – adenopathy, fever, sore throat
- Or, maybe only eye infection
- Highly contagious
- Spread by direct contact or contaminated surfaces
viral conjunctivitis: history
o Crusting in the morning
o Scratchy, burning, gritty, sandy feeling in the eyes
o Watery or “mucoserous” discharge
o May start in one eye, but usually second eye involved within 24-48 hours
o Often accompanied by other viral symptoms, URI
o Sick contacts (very contagious)
o Self-limiting process, worsening first 3-5 days, can last 1-2 weeks
viral conjunctivitis: exam findings
o Minor crusting
o Watery discharge; scant, stringy component which is mucus, not pus
o Pus does not appear spontaneously at the lid margin or in the corners of the eye
o Diffuse redness of the conjunctiva
o Signs/symptoms of viral URI (cough, runny nose, congestion)
o Absence of photophobia; able to keep eyes open
o Visual acuity intact
o May have ipsilateral (same side) preauricular lymphadenopathy
o Tarsal (palpebral) conjunctivae may have follicular or “bumpy” appearance
viral conjunctivitis: management
o Self-limiting; 1-2 weeks
o Highly contagious; wash hands frequently, do not share towels
o Cold compresses
o Artificial tears; put bottle in the fridge to soothe the eyes
o Topical antihistamine/decongestant
o Current EBP: no need for antibiotic ointment although patients will ask
Epidemic keratoconjunctivitis or EKC
- Subtype caused by adenovirus types 8, 19, & 37
- In addition to inflammation of the conjunctiva, keratosis (inflammation of the cornea)
- Symptoms include foreign body sensation which can be severe; reluctance to open the eye
- Visual acuity can be decreased by 2 or 3 lines
- Can be sight threatening, refer emergently
allergic, vernal, atopic conjunctivitis: s/s
- Itching – the cardinal symptom
- Redness – both eyes
- Morning crusting is possible
- Follicular or bumpy appearance to tarsal (palpebral) conjunctiva
- Other allergic symptoms – allergic rhinitis, asthma, atopic dermatitis in response to triggers
- Grass and ragweed pollen, dust mites, animal dander or feathers
- Sometimes profuse watery discharge
- On exam: diffuse injection
- Marked chemosis is possible
- If severe, may lead to corneal ulcers – requires referral
allergic, atopic, vernal conjunctivitis: management
o Allergen avoidance!!
o Non-Pharmacological:
* Cool compresses
* Refrigerated artificial tears
* Stop contact lens use while allergies are active
tx allergic, atopic, vernal conjunctivitis
o Mast cell stabilizers – cromolyn sodium, nedocromil
o Combination mast cell stabilizer/antihistamines (Olopatidine, azelastine) – these tend to work better
o Systemic therapies – oral antihistamines, e.g. loratidine, fexofenadine, cetirizine
o Topical cetirizine also mentioned in your book
o OTC topical vasoconstrictor/antihistamine combinations should only be used for up to 2 weeks to avoid rebound
o Topical glucocorticoids exist but I do not use these in my practice; would refer if refractory
o ** For someone who is using more than one type of eyedrop, apply 3-5 min apart to avoid the second medication washing out the first one.
Allergic Conjunctivitis in Contact Lens Wearers
- Giant papillary conjunctivitis (shown in pic)
- Contact lens deposits act as allergens; less common now with disposable lenses
- Can also occur in reaction to corneal sutures (overactive immune response in persons with atopy)
- Can also occur in persons with eye prosthesis
- Eversion of upper eyelid shows giant papillae
- I would refer this patient to ophthalmology!
Drug Induced Allergic Conjunctivitis
- Reaction to topical agents applied to the eyes or periorbital region; e.g. cosmetics, or ocular therapy
- Ocular ointments can cause this
- Beefy red colored conjunctiva, chemosis
- Again, would consult or refer
Bacterial Conjunctivitis: Rare in adults!
- Staphylococcus aureus - most common cause of acute bacterial conjunctivitis in adults
- Hemophilus influenza and Moraxella catarrhalis – more common causes of acute bacterial conjunctivitis in children
- More rarely - chlamydia, gonorrhea
- HIGHLY CONTAGIOUS!!
- Discharge persists throughout the day – thick and globular; can be yellow, white, or green
- Purulent discharge
Acute bacterial conjunctivitis
- Abrupt presentation with purulent drainage, but usually not painful, no photophobia
- Usually no visual deficit, unless from copious discharge
- Purulent discharge; persists throughout the day
- Injection; possibly chemosis
Chronic Bacterial Conjunctivitis
- Purulent discharge lasting longer than a few weeks, is usually due to chlamydia or dacryocystitis (inflammation of the lacrimal sac, usually secondary to blockage of the nasolacrimal duct)
- For this presentation the NP would refer the patient to a specialist
Hyperacute Bacterial Conjunctivitis
- Caused by gonorrhea; spread from genitalia, to hands, to eyes. Concurrent urethritis.
- Rapid onset of symptoms, within 12 hours of exposure
- Injection, eyelid edema, severe, continuous, copious purulent discharge, chemosis, pain or discomfort, tenderness to palpation, tender preauricular lymphadenopathy
- Frequent corneal involvement, can perforate
Bacterial Conjunctivitis: Topical treatments usually not necessary
- Self-limiting and topical treatment is not necessary.
- But Indicated for high risk patients: immunocompromised, health care workers, uncontrolled DM, hx glaucoma surgery
- Erythromycin Ophthalmic Ointment 1.25 cm (1/2 inch) applied to inner lower eyelid 4 times daily. May cause blurring
- Polymixin/trimethoprim drops, 1-2 drops 4 times daily – drops better for driving
- Duration of treatment: 5-7 days
- Alternative treatments: bacitracin ointment, sulfacetamide ointment, polymixin-bacitracin ointment, fluoroquinolone drops, azithromycin drops. If no improvement in 1-2 days would refer.
- Contact lens wearers: use glasses until sclera is white and at least 24 hours after antibiotic therapy is completed.
Bacterial Conjunctivitis: Systemic (oral or by injection) treatment is indicated for:
- H. Flu – amoxicillin-clavulanate
- Gonococcal – ceftriaxone 250 mg IM and 1 gram po of azithromycin
- Chlamydia – azithromycin, 1 gram po, or doxycycline, 100 mg po BID x 7 days
- Be sure to treat sexual partners of patients with chlamydial or gonococcal conjunctivitis
- Take home message here: When in doubt, consult
Blepharitis
- Chronic condition (eyelid and near eyelashes)
Blepharitis: presentation
o Burning and itchy eyes.
o Feeling of dryness.
o Eyelids are swollen in the morning, sometimes with crusting.
o Eyes feel gritty, sometimes with excessive tearing or blurring of vision.
Blepharitis: non pharm management
o Warm compresses
o Lid massage
o Lid washing
o Artifical tears
Blepharitis: pharm management
o For blepharitis caused by demodex mites, tea tree oil scrubs to the eyelashes
o Hypochlorous spray aka Avenova reduces bacterial load on the skin
Blepharitis: tx
If refractory, may use:
* Topical antibiotics – azithromycin or tobrex ophthalmic solution; erythromycin or bacitracin ointments (though they can cause contact dermatitis)
* Oral antibiotics – doxycycline, tetracycline, azithromycin, erythromycin in pregnancy or children
o Ophthalmologists may prescribe:
* Topical glucocorticoids – for oph’thy only
* Topical cyclosporine – again, for oph’thy only
Hordeolum: s/s
- Acute infection and inflammation of gland in the eyelid
- Tender
- Warm
- Erythematous
Hordeolum: tx
o Hot compresses
o OTC analgesics
Chalazion: s/s
- Painless lump on the eyelid
- Chronic, sterile, nontender
- May result from hordeolum which has not drained
- Bothers patients due to appearance; may obstruct vision
Chalazion: management
o Frequent hot compresses
o Practice good eyelid hygiene
o Referral to ophthalmologist
o Incision and curettage
o Glucocorticoid injection
o Scrub eyelids with washcloth moistened with warm water and baby shampoo; or expensive wipes
dry eye: etiology
o Multifactorial
o Defect in tear film due to meibomian gland dysfunction
o Poor eyelid closure
o Infrequent blinking
o Contact lens wear
o Caution: If the patient reports dry mouth or other systemic symptoms, consider further workup for Sjogren’s disease