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CPR > Heart Failure Drugs > Flashcards

Heart Failure Drugs Flashcards

1
Q

Furosemide

A

Family: Diuretic

MOA: inhibits NKCC2 pump

Clinical Use: edema, hypercalcemia, hypertension

SAE: hypokalemia, ototoxicity

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2
Q

Lisinopril

A

Family: RAAS drug

MOA: angiotensin converting enzyme inhibitor

Clinical Uses: CHF, HTN, diabetic renal disease

SAE: bradykinin cough reflex, hyperkalemia, teratogenic

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3
Q

Valsartan

A

Family: RAAS drug

MOA: angiotensin-II type I receptor antagonist

Clinical Uses: CHF, HTN

SAE: hyperkalemia, teratogenic

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4
Q

Spironolactone

A

Family: RAAS drug

MOA: aldosterone receptor antagonist

Clinical Uses: CHF, hyperaldosteronism, HTN

SAE: hyperkalemia, endocrine effects

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5
Q

Metoprolol

A

Family: beta blockers

MOA: B-1 adrenergic receptor antagonist

Clinical Uses: CHF, HTN, angina

SAE: bradycardia, AV block, CNS sedation

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6
Q

Carvedilol

A

Family: beta-blockers

MOA: mixed a-1 and b-adrenergic receptor antagonist

Clinical Uses: CHF, HTN, angina

SAE: bradycardia, AV block, CNS sedation

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7
Q

Hydralazine

A

Family: vasodilator

MOA: vascular K+ channel opener

Clinical Uses: CHF, angina

SAE: tachycardia, hypotension, HA

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8
Q

Isosorbid dinitrate

A

Family: vasodilator

MOA: nitric oxide mechanism

Clinical Uses: acute decompensated heart failure

SAE: tachycardia, hypotension, HA

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9
Q

Sacubitril

A

Family: vasodilator

MOA: neprilysin inhibitor

Clinical Uses: CHF

SAE: hyperkalemia, cough, hypotension

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10
Q

Digoxin

A

Family: inotrope

MOA: inhibit Na+/K+ ATPase

Clinical Uses: CHF, certain arrhythmias

SAE: arrhythmogenic, nausea, vision disturbances

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11
Q

Milrinone

A

Family: inotrope

MOA: phosphodiesterase III inhibitor

Clinical Uses: acute decompensated heart failure

SAE: arrhythmia

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12
Q

Dobutamine

A

Family: inotrope

MOA: B-1 adrenergic receptor agonist

Clinical Uses: acute decompensated heart failure

SAE: arrhythmia

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13
Q

Name 3 drugs from the RAAS family

A

Lisinopril, Valsartan, Spironolactone

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14
Q

Name 2 beta blockers used in heart failure

A

Metoprolol, Carvedilol

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15
Q

Name 3 vasodilator drugs used in heart failure

A

Hydralazine, Isosorbide dinitrate, Sacubitril

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16
Q

Name 3 inotropic drugs used in heart failure

A

Digoxin, Milrinone, Dobutamine

17
Q

This drug is active in the thick ascending limb of Henle and has a rapid onset of action.

A

Furosemide

Diuretic, acts on NKCC2 pump

18
Q

This RAAS drug triggers a bradykinin cough reflex.

A

Lisinopril

19
Q

This beta-blocker reduces mortality in HF patients.

A

Carvedilol

20
Q

These two vasodilators are often given in combination for HF.

A

Hydralazine and Isosorbide dinitrate

CPR (5 decks)

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