Arrhythmia Drugs Flashcards
Digoxin
Family: Cardiac Glycoside
MOA: inhibits Na+/K+ ATPase
Clinical Uses: CHF, atrial tachycardia
SAE: arrhythmias, vision
Procainamide
Family: Class IA
MOA: inhibits Na+ channels
Clinical Uses: atrial and ventricular tachycardias
SAE: arrhythmias
Lidocaine
Family: Class IB
MOA: inhibit Na+ channels
Clinical Uses: ventricular tachycardias
SAE: CNS
Flecainide
Family: Class IC
MOA: inhibit Na+ channels
Clinical Uses: atrial tachycardias in patients with normal
ventricular function
SAE: arrhythmias
Metoprolol
Family: Class II
MOA: inhibits beta-adrenergic receptors
Clinical Uses: atrial and ventricular tachycardias
SAE: —-
Amiodarone
Family: Class III
MOA: inhibit K+ and Na+ channels
Clinical Uses: atrial and ventricular arrhythmias
SAE: long QT, hypotensions, pulmonary fibrosis
Dronaderone
Family: Class III
MOA: inhibit K+ and Na+ channels
Clinical Uses: atrial and ventricular arrhythmias
SAE: long QT, depressed
Dofetilide
Family: Class III
MOA: inhibit K+ channels
Clinical Uses: atrial arrhythmias
SAE: long QT
Sotalol
Family: Class III
MOA: inhibit K+ channels and beta-adrenergic receptors
Clinical Uses: atrial and ventricular arrhythmias
SAE: long QT
Verapamil
Family: Class IV
MOA: voltage gated Ca2+ channel inhibitor, cardiac preferring
Clinical Uses: atrial arrhythmias > angina, HTN
SAE: hypotension, tachycardia
Nifedipine
Family: L-type Ca2+ channel blockers
MOA: voltage gated Ca2+ channel inhibitor, VSM preferring
Clinical Uses: angina HTN
SAE: hypotension tachycardia
Adenosine
Family: nucleotide receptor agonist
MOA: activated adenosine receptors
Clinical Uses: conversion of atrial arrhythmias
SAE: –
These two anti-arrhythmic drugs commonly have drug-drug interactions
Procainamide and Lidocaine
