ANS pharm Flashcards

1
Q

Dobutamine

A

β-1 and α-1 agonist

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2
Q

Dopamine

A

α and β agonist

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3
Q

Norepinephrine

A

α and β-1 agonist

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4
Q

Epinephrine

A

low dose – β-2 agonist

high dose – hits everything, esp α-1

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5
Q

Isoproterenol

A

non-selective β agonist

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6
Q

Clonidine

A

α-2 agonist

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7
Q

Methyldopa

A

α-2 agonist

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8
Q

Midodrine

A

α-1 agonist

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9
Q

Carvedilol

A

α-1 selective and β non-selective antagonist

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10
Q

Labetalol

A

β > α-1 antagonist

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11
Q

Doxazosine

A

α-1 antagonist

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12
Q

Metoprolol

A

β-1 antagonist

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13
Q

Propanolol

A

non-selective β-antagonist

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14
Q

Phentolamine

A

non-selective α antagonist

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15
Q

Phenoxylbenzamine

A

non-selective α antagonist

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16
Q

Atropine

A

non-selective muscarinic antagonist

17
Q

Pyridostigmine

A

reversible inhibitor of AChE

18
Q

What drug would you use for:

Bradycardia?

A

Isoproterenol

19
Q

What drug would you use for:

Chronic orthostatic hypotension due to autonomic insufficiency?

A

Midodrine

20
Q

What drug would you use for:

Acute hypotensive states?

A

Phenylephrine

Norepinephrine

21
Q

What drug would you use for:

Shock and heart failure

A

Dopamine

22
Q

What drug would you use for:

Acute heart failure

A

Dobutamine

23
Q

What drug would you use for:

reversal of vagal bradycardia?

A

Atropine

24
Q

What drug would you use for:

Treatment of neurogenic orthostatic hypotension?

A

Pyridostigmine

25
Q

Which ‘ol’ drug is a selective β antagonist?

A

Metoprolol, β-1 antagonist

26
Q

Which two adrenergic antagonists have uses with pheychromocytomas?

A

Phenoxylbenzamine and Labetalol

27
Q

This drug is sometimes called a “false neurotransmitter” because it is taken up and released from vesicles.

A

Methyldopa

28
Q

This drug targets a-2 receptors in CNS brainstem to decrease sympathetic outflow.

A

Clonidine

29
Q

At high doses, this drug looks like epinephrine

A

Dopamine

30
Q

Are dobutamine and atropine used in cardiac stress testing?

A

yep

31
Q

This drug is a neurotransmitter used by most postganglionic adrenergic fibers.

A

Norepinephrine

32
Q

Does norepinephrine cause a decrease in heart rate due to baroreflex increase in vagal tone?

A

Yep

33
Q

Can abrupt cessation of Clonidine cause a rebound HTN?

A

Yep, that’s unfortunate

34
Q

These two drugs are non-selective alpha antagonists

A

Phentolamine and Phenoxylbenzamine