ANS pharm Flashcards

1
Q

Dobutamine

A

β-1 and α-1 agonist

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2
Q

Dopamine

A

α and β agonist

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3
Q

Norepinephrine

A

α and β-1 agonist

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4
Q

Epinephrine

A

low dose – β-2 agonist

high dose – hits everything, esp α-1

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5
Q

Isoproterenol

A

non-selective β agonist

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6
Q

Clonidine

A

α-2 agonist

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7
Q

Methyldopa

A

α-2 agonist

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8
Q

Midodrine

A

α-1 agonist

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9
Q

Carvedilol

A

α-1 selective and β non-selective antagonist

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10
Q

Labetalol

A

β > α-1 antagonist

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11
Q

Doxazosine

A

α-1 antagonist

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12
Q

Metoprolol

A

β-1 antagonist

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13
Q

Propanolol

A

non-selective β-antagonist

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14
Q

Phentolamine

A

non-selective α antagonist

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15
Q

Phenoxylbenzamine

A

non-selective α antagonist

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16
Q

Atropine

A

non-selective muscarinic antagonist

17
Q

Pyridostigmine

A

reversible inhibitor of AChE

18
Q

What drug would you use for:

Bradycardia?

A

Isoproterenol

19
Q

What drug would you use for:

Chronic orthostatic hypotension due to autonomic insufficiency?

20
Q

What drug would you use for:

Acute hypotensive states?

A

Phenylephrine

Norepinephrine

21
Q

What drug would you use for:

Shock and heart failure

22
Q

What drug would you use for:

Acute heart failure

A

Dobutamine

23
Q

What drug would you use for:

reversal of vagal bradycardia?

24
Q

What drug would you use for:

Treatment of neurogenic orthostatic hypotension?

A

Pyridostigmine

25
Which 'ol' drug is a selective β antagonist?
Metoprolol, β-1 antagonist
26
Which two adrenergic antagonists have uses with pheychromocytomas?
Phenoxylbenzamine and Labetalol
27
This drug is sometimes called a "false neurotransmitter" because it is taken up and released from vesicles.
Methyldopa
28
This drug targets a-2 receptors in CNS brainstem to decrease sympathetic outflow.
Clonidine
29
At high doses, this drug looks like epinephrine
Dopamine
30
Are dobutamine and atropine used in cardiac stress testing?
yep
31
This drug is a neurotransmitter used by most postganglionic adrenergic fibers.
Norepinephrine
32
Does norepinephrine cause a decrease in heart rate due to baroreflex increase in vagal tone?
Yep
33
Can abrupt cessation of Clonidine cause a rebound HTN?
Yep, that's unfortunate
34
These two drugs are non-selective alpha antagonists
Phentolamine and Phenoxylbenzamine