Heart Failure Flashcards
Nicolas Norgard, PhD. (UMKC)
Ways to diagnose heart failure?

HFpEF

Neurohormonal model that drives heart failure

HFrEF

AHA HF Classification

NYHF Classification

Criteria for diagnosing heart failure

Brain Natriuretic Peptide (BNP)

First step in treatment of HF
Beta Blockers

Second step in treatment of HF
Vasodilating Beta Blockers

Choice of beta blockers to use for treatment of HF?
Carvedilol
Bisproprolol
Metoprolol succinate

Is carvedilol or metoprolol more effective?
Carvedilol

Temporal Effects of Beta Blocker Treatment in Heart Failure

Best way to dose beta blockers?

Uses of Ivabradine?

Add onto beta blockers if dose is maxed out

Third step in treatment of HF after beta blockers are on board?

Overview of the Renin-Angiotensin-Aldosterone System Blockade

Biological effects of angiotensin II?

Major effects of ACE inhibitors?

Dosing of ACE inhibitors?

When to use an angiotensin receptor blocker (ARB)?

Use of Neprilysin inhibitors?

Add onto an ARB, do not use with ACEi

Use of aldosterone antagonist?


Use of hydralazine and nitrates?


Effectiveness of hydralazine/Isorbide dinitrate among race?
Use in black patients:
- Added to, not substituted for ACE inhibitors or ARB
- Recommended for black HF patients who remain symptomatic despite optimal medical treatment
- Appropriate as first-line therapy in all HF patients unable to tolerate either an ACE inhibitor or ARB because of renal insufficiency, hyperkalemia, or possibly hypotension

Use of diuretics in HF patients?


Dosing of diuretics?

Mechanism of action in the kidney of loop and thiazide diuretics?

Appropriate treatment for the following patient?


Treatment for a patient that is experiencing over-diuresis?

Digoxin?

Risks of using digoxin?

Modes of death dependent upon HF classification?

What is Cardiac Resynchronization Therapy (CRT)

Implantable Cardioverter-Defibrillator (ICD)

Indication for Cardiac Resynchronization Therapy (CRT)?

Left ventricular assist device?

Specific contraindications for cardiac transplantation?


Treatment for Heart Failure with Reduced Ejection Fraction?
Risks…


Prevalence of Heart Failure with Preserved Ejection Fraction (HFpEF)?


Treatment of Heart Failure with Preserved Ejection Fraction (HFpEF)?


Acute heart failure syndromes (AHFS)

Medical management of AHFS is based on precipitating factors and clinical presentation

In patients experiencing a HF exacerbation requiring hospitalization:
Acute heart failure syndromes (AHFS)

Acute Heart Failure Syndromes: Medical management of AHFS is based on precipitating factors and clinical presentation

Monitoring with a Swan-Ganz Catheter?

How to help HF patients in the warm and wet category?


Treatment for HF patients in the cold and wet category?


Selection of an inotrope?

Effectiveness of different inotropes?

Flow chart for HF patients:
