Heart failure Flashcards

1
Q

heart failure definition

A

Complex clinical syndrome resulting from any structural or functional impairment of ventricular Unable to meet metabolic tissue requirements or cannot fill completely
or ejection of blood

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2
Q

HF w/ reduced EF (HFrEF)

A

EF ≤ 40%

pumping problem

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3
Q

HF w/ preserved EF (HFpEF)

A

EF ≥ 50%

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4
Q

Borderline hf

A

41%-49%

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5
Q

improved hf

A

> 40%

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6
Q

LV Diastolic Dysfunction

A

Delayed LV relaxation
Increased myocardial stiffness
Reduction in LV compliance
Restricted LV filling
LA HTN, LA systolic and diastolic dysfunction, pulmonary venous congestion, and exercise intolerance

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7
Q

LV systolic dysfunction

A

Contractility is reduced
Reduced SV
Increased LV end-systolic volume and end-diastolic volume
Compensatory LV dilation
Increased LV end diastolic pressure
Pulmonary venous congestion.

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8
Q

the hallmark of chronic LV systolic dysfunction

A

decreased ef < 40%

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9
Q

Class 1 diastolic hf

A

Class I - abnormal LV relaxation pattern with normal left atrial pressure

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10
Q

Class 2,3,4 diastolic hf

A

abnormal relaxation and reduced LV compliance resulting in an increase in LVEDP

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11
Q

Acute Decompensated HF

A

Worsening symptoms of preexisting condition

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12
Q

de novo acute HF

A

Sudden increase in intracardiac filling pressures and/or acute myocardial dysfunction

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13
Q

Chronic Heart Failure

A

Present in pts withlong-standingcardiac disease
Accompanied by venous congestion, but BP is maintained

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14
Q

Frank-starling relationship

A

SV is directly related to LVEDP
Magnitude of the increase in SV produced by changing the tension of ventricularmuscle fibers depends on myocardial contractility

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15
Q

Inotropic state

A
  • myocardial contractility as reflected by the velocity of contraction developed by cardiac muscle
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16
Q

Afterload

A
  • tension the ventricular muscle must develop to open the aortic or pulmonic valve
17
Q

Systolic HF and low CO causes SV to be …..

A

SV is fixed

18
Q

Diastolic HF HR

A

Tachycardia leads to decreased CO

19
Q

ANP

A

ANP stored in atrial muscle and released in increases in Atrial pressures

20
Q

BNP

A

BNP secreted by the atrial and ventricular myocardium

21
Q

ANP and BNP inhibit….

A

ANP and BNP inhibit cardiac hypertrophy and fibrosis

22
Q

earliest subjective finding of CHF

23
Q

concentric hypertrophy

A

pressure overload = thickened wall

24
Q

Early Cxray sign of LV fialure

A

Distention of the pulmonary veins in the upper lobes

25
Gold standard to Diagnose HF
TEE dx synmtoms pHF > 50% LVED dysfunction
26
Kerley lines
A- upper B = middle C = = lower lobes
27
BNP that correlates with HF diagnosis
BNP levels > 500 pg/mL – HF diagnosis (90% positive predictive value) 300 pg/mL - detecting dyspnea of cardiac origin
28
Labs that represent cardiac inflammatory factors
C-reactive proteins Growth differentiation factor 15
29
Class 1 HF
no S/s
30
Class 2 hf
slight limitations with physical acitivty
31
Class 3 HF
marked limitation of physical activity
32
Class 4 HF
pt is unable to perform physical acitvity
33
Class A HF
no evidence of cv dz
34
Class B HF
Evidence of minimal structural cv dz
35
Class C HF
Evidence of moderately severe structural c dz
36
Class D HF
Objective evidence of severe structural cv dz
37
Diuretics for HF
Thiazide and Loop First-line therapy for patients presenting in acute heart failure
38
Cardiac resynchronization therapy recommended for....
NYHA class III or IV LVEF < 35% QRS duration of 120–150 milliseconds
39
IABP causes....
Increases aortic diastolic blood pressure and coronary perfusion pressure Enhances LV ejection