Hearing Loss Flashcards
Which anatomical structures may be damaged in sensorineural hearing loss (SNHL)?
Hair cells of the organ of Corti in the cochlea
CNVIII
Auditory cortex
Give some examples of genetic causes of SNHL?
Huge number of syndromes:
- Connexin 26 GJB2 deafness
- Waardenburg’s
- Stickler
- Usher’s
- Pendred’s
Which antenatal factors might causes SNHL in a newborn?
Maternal infection –> rubella, chicken pox, HIV, CMV, streptococcus
Drug/alcohol misuse during pregnancy
What are some acquired causes of SNHL?
Presbyacusis Noise-induced hearing loss Inflammatory Trauma Autoimmune Tumours Meniere's disease Drugs
What is presbyacusis?
Age related high frequency SNHL
- loss of hair cells and neurones
What are the features of noise induced hearing loss?
Tinnitus common
Typically worst at 4kHz on audiogram
What are some causes of inflammatory SNHL?
Meningitis - important to identify in children who have had meningitis
What are the features of autoimmune SNHL?
Rapidly progressing, fluctuating, unilateral SNHL
Associated with vertigo and tinnitus
–> RA, GPA, sarcoidosis
Which tumours might cause SNHL?
Vestibular schwannoma
Meningioma
What are the features of a vestibular schwannoma?
Unilateral SNHL
What investigation should be done in a patient with unilateral SNHL?
MRI –> T1 weighted, gadolinium enhancement of CP angle + internal acoustic meatus
How is a vestibular schwannoma managed?
Yearly MRI to monitor for growth
If growing persistently:
- stereotactic radiosurgery
- surgical removal
What type of hearing loss is seen in Meniere’s?
Low frequency SNHL
Which drugs can cause SNHL?
Aminoglycosides e.g. gentamicin
Some chemotherapy agents
Which investigations should be done in someone presenting with hearing loss?
Pure tone audiogram (PTA) + Rinne/Weber
–> used in conjunction to see if SNHL or CHL
MRI if unilateral SNHL