Heamatology Flashcards
Normal values of RBCs count & HB concentration
HP = 12-16 gm/dl in females. & 13.5 - 17.5 gm/dl in males.
RBCs= 3.9-5 million/ul in females. & 4.5. 5 million/ul in males
Normal bleeding Time
< 9 minutes
Prolonged activated partial thromboplastin time(APTT)
[Normal=33-45sec]
Normal prothrombin time
[normal 12sec)
Normal platelet count is
250,000 - 400,000 / cmm
Causes of MCV’ is Increased = Macrocytic Hyperchromic anemia
Megaloblastic anemia :
- Folic acid deficiency
- B12 deficiency
Causes of MCV’ Normal = Normocytic Normochromic anemia
- Hemolytic anemia (except thalassemia)
- Aplastic anemia
- Acute bemorrhagic Anemia
Causes MCV Decreased = Microcytic Hypochromic anemia
- Iron deficiency anemia
- Anemia of chronic disease
- Thalassemia
Patient diagnosed as case of CA. Lung revived chemotherapy and he has chest infection and epistaxsis and anemia ? Aplastic anemia ¿
¿ How you confirmed the diagnosis ?
CBC: pancytopenia
Reticulocytopenia
Bone marrow aspiration : dry tap, biopsy
¿ Patient diagnosed as case of CA. Lung revived chemotherapy and he has chest infection and epistaxsis and anemia ?
A plastic anemia
Bone marrow suppressions
A Plastic Anemia
Which type of anemia if haemoglobin 8gm /dl and MCV below normal ?
Moderate Anemia
Which type of anemia if haemoglobin 7gm and MCV below normal
Sever Anemia
¿ Lady femal 35 years pregnant with hemoglobin gram and low MCV complaint of headaches fatiug pale skin atrophy of tongue papillae ?
¿ What do you think the diagnosis ?
If haemoglobin 8gram /dl and MCV below normal is iron deficiency anemia
¿ Lady femal 35 years pregnant with hemoglobin 8 gram and low MCV complaint of headaches fatiug pale skin atrophy of tongue papillae ?
If haemoglobin 8gram /dl and MCV below normal is iron deficiency anemia
? What investigation to be done to confirm the diagnosis ¿
Blood picture
Stool Iron studies :
- Low serum iron
- Low serum ferritin
¿ Lady femal 35 years pregnant with hemoglobin 8gram and low MCV complaint of headaches fatiug pale skin atrophy of tongue papillae ?
If haemoglobin 8gram /dl and MCV below normal is iron deficiency anemia
? Management ¿
Treat cause of blood loss
Given ( iron )oral intake/injection
¿ Koilonychia ( spoon shaped nail ) seen in ?
iron deficiency anemia
¿ Mild jaundice found in ?
Haemolytic anemia
? Causes of iron deficiency ¿
1/ poor intake
2/ decreed absorption
3/ Increase demand
4/ blood loss (common cause)
It is an autoimmune disorder in which there is atrophic gastritis with loss
parietal cells in the gastric mucosa with consequent failure of intrinsic factor production and vitamin B malabsorption , common in fair haired and blue eyes , A blood group , females more than males
Pernicious anaemia
¿ Pernicious anaemia associated with ?
Autoimmune diseases , thyroid disease & vitiligo , gastric carcinoma with PA
¿ Parietal cell antibodies are present in ?
90% of patients
¿ Intrinsic factor antibodies found in only ?
50% of patient
¿ Anemia , red sore tongue ( glossitis ) angular stomatitis ? Are clinical features of ¿
Pernicious anemia
