Healing & Repair Flashcards

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1
Q

What is the difference between regeneration and repair?

A

Regeneration - restoring infected tissue (Acute inflammation)

Repair - Repairing tissue (chronic inflammation)

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2
Q

What is Regeneration?

A

replacement of current damaged cells with functional, differentiated cells

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3
Q

What is repair?

A

Production of a fibrous scar and changes in tissue structure

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4
Q

What are the cell types in regeneration & repair?

A
  • Labile cells; Rapid regeneration/active state is cell division)
  • Stable cells (conditional renewal cells); variable rates of regeneration
  • Permanent cells; unable to divide/regenerate
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5
Q

What are the 4 stages in healing?

A

1) Clotting & Coagulation
2) Inflammatory cell migration
3) Proliferative phase - fibroblast migration, formation granulation tissue & angiogenesis
4) Maturation phase - Tissue remodelling

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6
Q

Whats the difference between primary & secondary intentions?

A

Primary intention - Small wound, rapid healing, minimal tissue loss

Secondary intention - Large wounds, scar formation, healing takes longer and greater tissue loss

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