head and neck cancer Flashcards

1
Q

they are usually

A

squamous cell carcinomas

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2
Q

potential areas

A
nasal cavity 
paranasal sinuses
mouth 
salivary glands
pharynx
larynx
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3
Q

spread

A

usually spread to lymph nodes first

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4
Q

risk factors

A
smoking 
chewing tobacco 
alcohol 
EBV
chewing betel quid
HPV esp 16
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5
Q

red flags

A
lump in mouth or lip 
unexplained mouth ulceration >3wks
erythroplakia 
erythroleukoplakia 
persistent neck lump 
unexplained voice hoarsness
unexplained thyroid lump
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6
Q

Mx

A

MDT
cetuximab
chemo, radio-therapy
surgery

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7
Q

cetuximab

A

monoclonal antibody used to treat squamous cell carcinoma H&N

targets epidermal growth factor receptor

can also be used in bowel cancer

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