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BAB1 week 2 > HC.5: Regulatie bloeddruk > Flashcards

HC.5: Regulatie bloeddruk Flashcards

1
Q

Adrenerge receptoren

A

a-adrenoceptor: a1, a2
- Affiniteit: noradrenaline > adrenaline . isoprenaline
B-adrenoceptor: B1
- Affiniteit: isoprenaline > adrenaline > noradrenaline
B-adrenoceptor: B2
- Affiniteit: isoprenaline > adrenaline

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2
Q

a1-adrenoceptor agonisten

A

Adrenaline
Noradrenaline
Fenylephrine

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3
Q

Farmacologische effecten a1 agonisten

A

Vasoconstrictie
Verhoging perifere weerstand
Verhoging bloeddruk
Mydriasis
Sluiting van urineblaas sphincter

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4
Q

Therapeutisch gebruik a1 agonisten

A

Lokale bloeding
Verkoudheid
Inductie mydriasis
Verlenging werking lokale anaesthetica
Shock

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5
Q

a2-adrenoceptor agonisten

A

Adrenaline
Noradrenaline
Clonidine

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6
Q

Farmacologische effecten a2 agonisten

A

Verminderde transmitter afgifte
Vasoconstrictie
Veminderde insuline afgifte

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7
Q

B1-adrenoceptor agonisten

A

Adrenaline
Noradrenaline
Isoprenaline
Dobutamine

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8
Q

Farmacologische effecten B1 agonisten

A

Hartfrequentie omhoog
Hartcontractiliteit omhoog
Geleiding in het hart omhoog
Renine afgifte omhoog

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9
Q

Therapeutisch gebruik B1 agonisten

A

Hartstilstand
Hartblok

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10
Q

B2-adrenoceptor agonisten

A

Adrenaline
Isoprenaline
Salbutamol

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11
Q

Farmacologische effecten B2 agonisten

A

Vaatverwijding
Perifere weerstand omlaag
Verslapping bronchi
Verslapping baarmoeder
Glycogerolyse in spieren en lever omhoog
Glucagon afgifte omhoog

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12
Q

Therapeutisch gebruik B2 agonisten

A

Astma
Dreigende vroeggeboorte

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13
Q

a1-adrenoceptor antagonisten

A

Fentolamine
Phenoxybenzamine
Prazosine
Doxazosine

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14
Q

Farmacologische effecten a1 antagonisten

A

Vasodilatatie
Perifere weerstand omlaag
Bloeddruk omlaag
Relaxatie prostaat
Relaxatie urineblaas sphincter

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15
Q

Therapeutisch gebruik a1 antagonisten

A

Hypertensie
Prostaat hypertrofie
Phaeochromocytoom
Perifeer vaatlijden
Impotentie

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16
Q

a2-adrenoceptor antagonisten

A

Fentolamine
Phenoxybenzamine
Yohimbine

17
Q

Farmacologische effecten a2 antagonisten

A

Transmitter afgifte omhoog
Insuline afgifte omhoog

18
Q

B1-andrenoceptor antagonisten

A

Propranolol
Pindolol
Atendol
Metoprolol

19
Q

Farmacologische effecten B1 antagonisten

A

Hartslag omlaag
Hartcontractiliteit omlaag
Vertraging hartgeleiding
Renine afgifte omlaag

20
Q

Therapeutisch gebruik B1 antagonisten

A

Hartritmestoornissen
Secundaire preventie hartinfarct
Angina pectoris
Hypertensie
Migraine profylaxe
Angsttremoren
Glaucoom

21
Q

Therapeutisch gebruik Labetalol

A

Phaeochromocytoom
Hypertensie crisis

BAB1 week 2 (10 decks)

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