HC 2 Flashcards
Why should we use EEG?
-Reaction time is the ultimate result of sensory, decision and motoric processes.
-We don’t know what happens in the brain during these processes. EEG helps determine the stadia with this.
-EEG can time course these stadia with precision of miliseconds.
-EEG can inform us about cognitive processes if there is no behavioural response.
What is an advantage of EEG compared to fMRI?
There is high temporal resolution, because of the distinction in stadia of informationprocessing. This is very hard or near impossible when using slow hemodynamic signals (fMRI).
For appliances that require real-time control, the high temporal resolution is needed.
ERPs allow us to measure all the different stadia, while in fMRI there are collapsed into a single time slice.
What is measured by EEG?
The electrical signal that is produced by cerebral activity. The most important one being the postsynaptic potential in the apical dendrites from cortical pyramidneurons.
Why do we not measure action potentials with EEG?
Action potentials only go in one direction. They are all or none responses and always excitory. This means that they cannot be summed up and they also don’t last long.
Why are post-synaptic potentials better picked up than action potentials by the EEG?
-They are great at responses
-Last longer
-Weaker in amplitude
-When travelling together they create dipoles at pyramidal cells
-Can be inhibitory or excitory
-Can be summed up
Why can neurons from the amygdala not be measured with the EEG?
It is important that the potentials go in the same direction, which is not the case for the amygdala. This structure has neurons where the sum is near 0, because the potentials cancel each other out.
What are the requirements for a strong EEG signal?
They have to summed over many neurons, meaning:
-Timing, they have to be harmonized
-Position of the neuron, when they are aligned in the same orientation, there is a more powerfull EEG, if not then the signal gets neutralised.
In this way, positive and negative potentials don’t cancel each other out when they get summed.
Which cells have the right properties for a strong EEG signal?
Pyramidal Cells in the cortex.
What are dipoles?
It is a seperation charge over distance. It is essential for EEG, because dipole orientation provides differentiation among sources.
What does an EEG set-up look like?
The EEG set-up looks like:
-Participants sits in front of the stimulation computer
-EEG is measured while the participant fixates on the screen
-The EEG signal goes through filters and amplifiers
-The marker codes and also the filtered and amplified EEG signal is put into a digitization computer
What are triggers (markers)?
They are the stimuli that are marked with a certain code, for example congruent or incongruent and they precede the responses, which also have their own code.
What is a mastoid?
It is the thickest part of the skull and is usually used as a reference sensor in EEG.
How is EEG measured?
The voltage level between two sensors is measured. This is usually between one sensor on the scalp and a reference one.
The positiveness or negativeness of a voltage level determines how the signal looks. In other words: this results in rhythmic fluctations in voltage.
Name the reference and ground electrodes and where are they located?
Ground electrode: On the forehead
Reference:
Tip of the nose
Nasal cavity
Earlobe
Mastoid
What is a reference electrode?
The fundamental principle is: always think of ERPs as a difference between the active and reference sites.
It provides a biological baseline.
How should you place the reference electrode?
It should be in a convenient location:
-Not biased towards a certain hemisphere
-Easy to attach
-Not distracting
-Frequently used by other investigators so that waveforms can be easily compared
The best compromise according to Luck in most cases is the average of mastoids (or earlobes), but other researchers believe average reference is the best.
What is the difference between the international 10-20 system and 10-10 system?
The distance between each sensors and the amount of electrodes. The 10-20 system has less sensors and the 10 and 20 refers to distances between adjacent electrodes, which are either 10% or 20% of the total distance of the skull (front to back or left to right or circumference of the head).
The use of percentages guarantees that the location of a particular electrode is the same across participants, independent of size of the head.