HBV

Question 1

Disease

Answer 1

HBV, liver carcinoma

Question 2

Transmission

Answer 2

Blood transfusion
Intercourse
Small cuts
Surgery
During birth

Question 3

Characteristics

Answer 3

Envelope virus
PdsDNA
RT activity
Present in the form of sphere and filaments

Different type of genes:

S-gene ( surface gene ) :
-used as marker for identification
- Involve in vaccination of HBV

C-Gene ( core gene) :
Nucleic acid production

E-gene ( transmission ):
-production of e-antigen
-transfer from person from to another

X-gene ( x protein)
Imp in mrna ( late and early protein)

P-gene (polymerase activity)
Dna formation

Question 4

Pathogenisis

Answer 4

From blood to liver then Hide and then damage hepatocytes then liver regenerates then virus kill more then liver regenerate again proliferation occurs then cancer

Question 5

Symptoms

Answer 5

Jaundice
Fever
Pale skin
Myalgia

Question 6

Lab diagnosis

Answer 6

Surface anti gen
No initial anti body check
Core antigen check
E antigen check

Question 7

Treatment

Answer 7

Alpha-interferon ( short half life )
PEG-interferon ( long half life

Question 8

Prevention

Answer 8

Active and passive imunnization