HAV Flashcards
1
Q
Disease
A
HAV, Jaundice
2
Q
Characteristics
A
Non-envelope virus
+RNA virus
Not Involve in liver carcinoma
3
Q
Transmission
A
Fecal-oral route
Unclean water
Poor hygiene
4
Q
Replicative cycle
A
Attachment, penetration, uncoating, genome replication, + RNA - RNA
5
Q
Pathogenisis
A
Multiply in GIT ( small intestine)
Absorbed and enter into blood
Enter liver by hepatic liver vein
Hepatocytes
Cause inflammation
Cytopathic effect: cause no death to hepatocytes and does not lead to carcinoma
6
Q
Lab diagnosis
A
Primary antibodies IgM
IgG level
7
Q
Symptoms
A
Jaundice : pale skin, weight loss, dark urine
8
Q
Treatment
A
Passive and active immunization
