Hart ontwikkeling III Flashcards

1
Q

Wat zijn de kenmerken van de AV-kanalen?

A
  • Connecteerd en aligns de hartkamers
  • Vormt septums en valves
  • Valve function
  • Vertraging van elektrische impuls
  • Vormt AV knoop/AV conduction system
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2
Q

Waar is Tbx2-enhancer kamer-specifieke repressie afhankelijk van?

A

GATA-sites

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3
Q

Waar komt GATA tot expressie?

A

In alle myocyten

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4
Q

Wat doen HDACs?

A

Mediate chamber-specific histone deacetylation and repression

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5
Q

Waar is BMP2 in AV-kanaal voor nodig?

A
  • Mesenchymale cushion formation
  • Tbx2 en 3 gen activiteit
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6
Q

Waar is BMP signalering breed actief?

A

In de hartbuis

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