Hard drugs πŸ’Š Flashcards

1
Q

Somatostatin analogue

A

Octreotide

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2
Q

Tamoxifen mode of action (cancer treatment)

A

selective oestrogen receptor modulator

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3
Q

Cellulitis treatment

A

flucloxacillin

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4
Q

Drug that inhibits prostaglandin production

A

Asprin

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5
Q

Staph aureus treatment

A

Flucloxacillin

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6
Q

Atropine mode of action

A

antimuscarinic

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7
Q

What type of receptors does adrenaline act on

A

G protein-coupled receptors

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8
Q

May cause gout

A

Thiazides

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9
Q

Furosemide drug class

A

Loop diuretic (inhibits the Na-K-Cl cotransporter)

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10
Q

May affect growth if used in young children

A

Inhaled corticosteroids

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11
Q

Inhibits the Na-K-Cl cotransporter in the thick ascending limb of the loop of Helne

A

Furosemide

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12
Q

Used in management of stable adult asthma for those not controlled with a SABA + ICS

A

Leukotriene receptor antagonists

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13
Q

Inhibit peptidoglycan cross linking

A

Cephalosporins

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14
Q

Adenosine and beta blocker contraindication

A

Asthma

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15
Q

Drug contraindication to concurrent verapamil therapy

A

Beta blockers

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16
Q

Amiodarone side effect

A

Bradycardia

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17
Q

Amlodipine side effect

A

Headache

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18
Q

Impotence is a side effect of

A

Beta blockers

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19
Q

Destroys amoxycillin

A

Beta lactamase

20
Q

Treatment for anaerobic infections

A

Metronidazole

21
Q

Inhibit protein synthesis by acting on the 30S subunit of ribosomes

A

Aminoglycosides and tetracyclines

22
Q

Treatment for infective exacerbation of COPD

A

iSOAP: ipratropium, salbutamol, oxygen, amoxicillin, prednisolone

23
Q

Diuretic for ascites

A

Spironolactone

24
Q

All patients post MI should be started on

A

ACE-inhibitor, beta-blocker, high intensity statin, anti-platelet therapy

25
Q

Reduce variceal bleeding

A

Beta-blockers (propanolol)

26
Q

drug ending in -dipine e.g. amlodipine

A

Calcium channel blocker

27
Q

drug ending in -olol e.g. propranolol

A

beta-blocker

28
Q

drug ending in -pril e.g.ramipril

A

ACE inhibitor

29
Q

drug ending in -sartan e.g. losartan

A

ARB

30
Q

Steps of hypertension management

A
  1. A or B, unless >55 or black -> C
  2. A + C, if black ARB instead of A. D if C not tolerated
  3. A + C + D
  4. A + C + D + D (extra thiazide/ spironolactone)
31
Q

Treatment for peptic ulcers

A

Antacids, H2 antagonists, PPI

32
Q

Uc/crohn’s treatment steps

A

5-ASA
Steroids
Immunosuppression
Anti-TNF drugs

33
Q

Anti-diarrhoeal

A

Loperamide

34
Q

Drug class that blocks the enzyme that inserts the viral genome into the DNA of the host cell

A

Integrase inhibitors (β€œgravirs”)

35
Q

Important cause of agranulocytosis

A

Clozapine

36
Q

Targets protein synthesis in bacteria

A

Erythromycin

37
Q

Inhibit sodium reabsorption by blocking the Na+Cl- symporter at the beginning of the distal convoluted tubule

A

Thiazides

38
Q

Blocks NMDA receptors

A

Ketamine

39
Q

Anti-platelet, decreases formation of thromboxane A2 resulting in decreased platelet aggregation

A

Aspirin

40
Q

Metronidazole mode of action

A

Damages DNA

41
Q

Gentamicin drug class

A

Animoglycoside

42
Q

How does adrenaline treat anaphylaxis

A

by acting on alpha-adrenergic receptors and causing vasoconstriction

43
Q

____ are a cause of impaired glucose tolerance

A

Thiazides

44
Q

Monoclonal antibody drugs typically end in

A

β€˜-mab’

stands for Monoclonal AntiBody.

45
Q

Troponin I binds to ___ to hold the troponin-tropomyosin complex in place

A

actin

46
Q

Why is heparin classed as a low volume drug

A

It has a low volume of distribution