Hand problems Flashcards
Epidemiology of dupuytrens?
> Age 15-64 - M:F = 8:1
Age >75 - M-F = 2:1
> Disease develops earlier in men > Autosomal dominant, varied penetrance > Sporadic in 30% cases > White race almost exclusively > Associative factors (Diabetes, alcohol, tobacco, HIV, Epilepsy)
Associations with Dupuytren’s?
> Diabetes > Alcohol > Tobacco > HIV > Epilepsy
Which race is more likely to get Dupuytren’s?
White
Which sex is more likely to get Dupuytren’s?
Male
> Age 15-64 - M:F = 8:1
> Age >75 - M-F = 2:1
Dupuytren’s diathesis?
> Early onset disease
Bilateral disease
Family History
Ectopic disease
Dupuytren’s pathology?
Myofibroblast:
> Intracellular contractile elements
> Regulated by growth factors
> Production of collagen
Dupuytren’s - functional problems?
> Usually not painful > Loss of finger extension – active or passive > Hand in pocket > Gripping things > Washing face
Dupuytren’s - treatment options?
Non-operative
> Observe
> Splints don’t work
> Radiotherapy
Operative > Partial fasciectomy > Dermo-fasciectomy > Arthrodesis > Amputation
> Percutaneous Needle Fasciotomy
Collagenase
Dupuytren’s - non-operative treatment options?
Non-operative
> Observe
> Splints don’t work
> Radiotherapy
Dupuytren’s - operative treatment options?
Operative > Partial fasciectomy > Dermo-fasciectomy > Arthrodesis > Amputation
> Percutaneous Needle Fasciotomy
Collagenase
What is the most common procedure performed in the UK?
Partial fasciectomy
How long does it take for the wound to heal in partial fasciotomy?
2-3 weeks
Why is physiotherapy required in Dupuytren’s?
For stiffness
Can Dupuytren’s be cured?
No
What is the reoccurrence rates of Dupuytren’s after partial fasciectomy?
50% at 5 years
What is the advantage and disadvantages of dermo-fasciotomy in Dupuytrens?
Advantage:
> Removal skin may reduce reoccurrence
Disadvantages:
>More radical procedure
> Requires intensive physiotherapy
What is the advantage and disadvantages of percutaneous needle fasciotomy in Dupuytrens?
Advantages: > Quick > No wounds > Return to normal activities 2-3 days > Can be repeated > Does not prevent traditional surgery in future
Disadvantages:
> Higher recurrence
(? 50% at 3 years)
> Risk of Nerve Injury
What is the advantage and disadvantages collagenase in Dupuytrens?
> Presented 3 year recurrence rate 34.8%
3 Flexor Tendon Ruptures!
Cost
Await longer term recurrence rates
How many tendons to each finger?
Two tendons to each finger
What is the significance of the tendons of the fingers running within a sheath
> Keep tendon close to bone
Thickens in sheath = pulley
Swelling in tendon catches on pulley