Hallucinogens: Norepinephrine and GABA Enhancers-GABA Enhancers

Question 1

GABA Enhancers

Answer 1

-Inhibits synaptic transmission in the central nervous system

Question 2

Fly Agaric

BOTANICAL INFORMATION:

Answer 2

• Mushroom
• Boreal North-temperatures
• Eurasia and North America

Question 3

Fly Agaric

HISTORY AS A MEDICINAL PLANT:

Answer 3

• Hallucinogen-Asia and Scandinavia and North America
• Indigenous tribes used for shamanistic purposes, divination rites, contact the spirit world, diagnose illnesses, recreational purposes
• Fresh or dried
• Ceremonial drinking of the urine of mushroom eaters

Question 4

Fly Agaric

MODERN UTILIZATION:

Answer 4

• Muscimol andIbotenic acid
  
  • GABA receptor agonist, sedating effect
  • Stimulates receptors of glutamate, synaptic connections in the brain, delirium effect
• Symptoms-reddening of the skin, slurred speech, seizures, nausea, vomiting, coma-like sleep, persistent severe headache pain
• Lethal
• Wasson-“soma” in Ayurvdic, Aryans
  
  • Evidence some is wild rue-weedy plant in Asia, alkaloids harmine and harmaline