Hallmarks of Cell injury continued Flashcards

1
Q

See diagram with cell injury

A
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2
Q

If we don’t rectify condition we can get

A

hypertropy of heart

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3
Q

Autophagy

A

cells eat from inside out

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4
Q

lysomes eat

A

from inside out

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5
Q

karolysis

A
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6
Q

karorrhexis

A

breaking apart the karyotype of chromosomes within the nuculeus

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7
Q

endometrial lining

A

uterus proliferates to adapt, increase number of cells due to estrogen and progesterone thats produced during the menstrual cycle

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8
Q

Hyperplasia

A

increase number of cells

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9
Q

Menstruation

A

shedding, normal signal

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10
Q

atrophy

A

reduction in size

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11
Q

hypertrophy

A

cells get bigger

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12
Q

hyperplasia

A

plasia means cell division, proliferation and division

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13
Q

metaplasia

A

cells covert from one cell to another

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14
Q

dysplasia

A

disorganization

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15
Q

The plasia are reversible but

A

increase cancer risk

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16
Q

atrophy

A

May be physilogic or pathologic

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17
Q

Enometrial cells shrink

A

they atrophy due to lack of hormones and under go cell death

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18
Q

Pathologic

A

frontal lobe, brain atrophy, arm in cast

19
Q

denervation atrophy

A

loss of nerve due to injury or damage

20
Q

ischemic atrophy

A

loss of blood and nutrients

21
Q

hormonal stimulation

22
Q

hypertrophy

A

increase in cell size in response to stress

23
Q

cross section of heart

A

long standing htn, see thickening

24
Q

hormonal stimulation

A

see under pregnancy, or in a muscle for demand

25
hormonal stimulation
can be patholoic or excessive
26
cardiac myocytes
terminally diff
27
Endometrial lining of uterus
under go hyperplasia
28
Psoriasis
thking of epidermis see pic
29
metaplasia
one cell replaces another by an immature cell
30
Metaplasia is
a reversible process
31
See metaplasia in
epitheal and connective tissue
32
Metaplasia
increased risk for cancer
33
cigarette smoking see
columnar or cilated epithelial cells with epithelial cells
34
Mutagens and toxins get into lungs
increase risk for cancer
35
endocervix see pic
see squamous metaplasia
36
endocervix see ex
squamous metaplasia, eg cervical cancer
37
endocervix see eg
squamous metaplasia, eg cervical cancer
38
dysplasia
disorganized growth and maturation of cellular components, seen in hyperplastic type squamous epithelial where epidermal increase with the son
39
ulcerative colitis , cervix, pap
dysplastic cells, not cancer but, increase risk
40
Dysplastic cells need to be removed or abated
due to increase risk
41
HPV
cervical cancer
42
If a person stops smoking
you can return the cells back to columunar cilated form. Shares alot of cytologic features with cancer.
43
You want to remove dysplastic cells that
increase cancer risk