Hallmarks of Cell injury continued Flashcards

1
Q

See diagram with cell injury

A
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2
Q

If we don’t rectify condition we can get

A

hypertropy of heart

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3
Q

Autophagy

A

cells eat from inside out

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4
Q

lysomes eat

A

from inside out

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5
Q

karolysis

A
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6
Q

karorrhexis

A

breaking apart the karyotype of chromosomes within the nuculeus

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7
Q

endometrial lining

A

uterus proliferates to adapt, increase number of cells due to estrogen and progesterone thats produced during the menstrual cycle

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8
Q

Hyperplasia

A

increase number of cells

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9
Q

Menstruation

A

shedding, normal signal

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10
Q

atrophy

A

reduction in size

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11
Q

hypertrophy

A

cells get bigger

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12
Q

hyperplasia

A

plasia means cell division, proliferation and division

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13
Q

metaplasia

A

cells covert from one cell to another

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14
Q

dysplasia

A

disorganization

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15
Q

The plasia are reversible but

A

increase cancer risk

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16
Q

atrophy

A

May be physilogic or pathologic

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17
Q

Enometrial cells shrink

A

they atrophy due to lack of hormones and under go cell death

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18
Q

Pathologic

A

frontal lobe, brain atrophy, arm in cast

19
Q

denervation atrophy

A

loss of nerve due to injury or damage

20
Q

ischemic atrophy

A

loss of blood and nutrients

21
Q

hormonal stimulation

A

atrophy

22
Q

hypertrophy

A

increase in cell size in response to stress

23
Q

cross section of heart

A

long standing htn, see thickening

24
Q

hormonal stimulation

A

see under pregnancy, or in a muscle for demand

25
Q

hormonal stimulation

A

can be patholoic or excessive

26
Q

cardiac myocytes

A

terminally diff

27
Q

Endometrial lining of uterus

A

under go hyperplasia

28
Q

Psoriasis

A

thking of epidermis see pic

29
Q

metaplasia

A

one cell replaces another by an immature cell

30
Q

Metaplasia is

A

a reversible process

31
Q

See metaplasia in

A

epitheal and connective tissue

32
Q

Metaplasia

A

increased risk for cancer

33
Q

cigarette smoking see

A

columnar or cilated epithelial cells with epithelial cells

34
Q

Mutagens and toxins get into lungs

A

increase risk for cancer

35
Q

endocervix see pic

A

see squamous metaplasia

36
Q

endocervix see ex

A

squamous metaplasia, eg cervical cancer

37
Q

endocervix see eg

A

squamous metaplasia, eg cervical cancer

38
Q

dysplasia

A

disorganized growth and maturation of cellular components, seen in hyperplastic type squamous epithelial where epidermal increase with the son

39
Q

ulcerative colitis , cervix, pap

A

dysplastic cells, not cancer but, increase risk

40
Q

Dysplastic cells need to be removed or abated

A

due to increase risk

41
Q

HPV

A

cervical cancer

42
Q

If a person stops smoking

A

you can return the cells back to columunar cilated form. Shares alot of cytologic features with cancer.

43
Q

You want to remove dysplastic cells that

A

increase cancer risk