Hallmarks Flashcards
Compiled hallmarks/gold standards/definitions
presence of elongated, biconvex
transparent, needle shaped clefts which
represent chole crystals dissolved
during tissue processing
Atheroembolic disease
hallmark of APAS that is almost invariably
predictive of a poor outcome.
Livedo reticularis
Presence of patchy inflxy
infiltrates within interstititum (m.c. deep
cortex and outer medulla
AIN
infiltration of
inflammatory cells with associated edema,
which usually spares glomeruli and blood
vessels.
AIN
Loss of apical brush border of Prox Tub
cells is the Hallmark finding in
ATN
Unprovoked Hypokalemia
Hyperaldosteronism
hallmark renal
vascular lesionin px with uncomplicated
primary HPN
Afferent Arteriolar narrowing
an abnormal thirst
response in addition to variable defects in
AVP secretion
OSMORECEPTOR
DYSFUNCTION
urinary sodium (UNa) in reduced EABV
less than 15-20 mmol/L
inability to acidify the
urine appropriately during spontaneous or
chemically induced metabolic acidosis
classical hypokalemic distal
RTA
The pathologic sine qua non of minimal
change glomerulopathy
effacement of
visceral epithelial cell foot processes
observed by electron microscopy
ubiquitous clinical feature of the syndrome
is proteinuria which may be nephrotic or
nonnephrotic
FSGS
ubiquitous pathologic feature is focal
segmental glomerular consolidation or
scarring, which may have several distinctive
pattern
fsgs
mesangial interposition into an expanded
subendothelial zone that contains electrondense
immune complex deposit
Type 1 MPGN
The hallmark ultrastructural feature of PSGN
subepithelial humplike dense deposits
ubiquitous ultrastructural finding is
mesangial electron-dense deposits that
correspond to the immune deposits seen by
immunohistologic analysis
IgA
Best diagnostic modality to dx papillary
necrosis in SC
IVP
Gold standard for
identifying TRAS
DIGITAL intraarterial contrast
angiography
golden standard- for
definition of vasc ana and stenotic
lesions in kidney
Intraarteral angio
Vit D assay gold standard
HPLC
diagnostic procedure of
choice for nephrolith
CT scan
familial
hyperaldosteronism type I
Glucocorticoid-Remediable
Hyperaldosteronism
Gordon’s Syndrome, Familial
Hyperkalemic Hypertension
Pseudohypoaldosteronism Type 2
loss of function of EnAc
Pseudohypoaldosteronism Type 1
medial thickening and calcification of smaller elastic arteries
Mönckeberg’s calcification
white lines or
keukonychia can develop during marked
hypoalbuminemia
Muehrcke’s lines
chronic
hypoalbuminemia may cause more
difuse white nail
Terry’s or half and half nails
confer a peculiar susceptibility to the
vascular effects of gram-negative
endotoxin
Shwartzman phenomenon
autosomal
dominant mutation of KCNJ2 encoding
Kir 2.1 (periodic paralyisis, cardiac
arrhythmia, dysmorphic features
Andersen’s syndrome
renal compression by a
subcapsular mass or hematoma with
hyperreninemia)
Page kidney
