Half-Lives and More Flashcards

1
Q

F18-FDG

Production?

Half-Life?

Decay?

Energy?

A
  • Cyclotron
  • 109.7 minutes. (110 minutes)
  • Beta plus decay
  • 511 KeV
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2
Q

I-123 NaI

Half Life?

Energy?

Production?

Decay?

A
  • 13 hours (take out the two)
  • “low energy” 159 KeV (close to Tc-99m)
  • Cyclotron produced
  • electron capture
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3
Q

Ga-67 citrate

Half-life?

Production?

Analog?

Decay?

Energy?

A
  • 78 hours
  • Cyclotron
  • Iron analog
  • electron capture
  • 100, 200, 300, 400
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4
Q

What is the half-life of Ga-68 DOTATATE (NETSPOT)?

A

The half-life of Ga-68 is 68 minutes. Ga-68 DOTATATE (NETSPOT) is a PET agent that is used in neuroendocrine tumor imaging. Ga-68 DOTATATE binds to somatostatin receptors with highest affinity for subtype 2 receptors (SSTR2). It binds to cells that express somatostatin receptors, including malignant cells, which overexpress SSTR2 receptors. Ga-68 is a β+ emitting radionuclide, which allows for PET imaging.

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5
Q

Low Energy Collimator Radionuclides

A
  • Tc-99m
  • Xe-133
  • Tl-201
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6
Q

Medium Energy Collimator Radionuclides

A
  • In-111
  • Ga-67
  • I-123
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7
Q

High Energy Collimator Radionuclides

A
  • I-131
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8
Q

Tc-99m

Half-life?

Production?

Energy?

Decay?

A
  • 6 hours
  • 99Mo Generator
  • “Low energy” 140 KeV
  • IT decay
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9
Q

Xe-133

Half life?

Energy?

Production?

Decay?

A
  • 125 hours (biologic is 30 seconds)
  • “low energy” 81 KeV
  • Nuclear Reactor
  • Beta minus decay
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10
Q

Thallium-201

Analog?

Half-Life?

Energy?

Production?

Decay?

A
  • Potassium analog
  • 73 hours
  • 135 and 167 keV are gamma rays, but MAJOR imaging contribution is from decay to Mercury 201 via electron capture releasing 69 and 81 keV XRAYS.
  • cyclotron
  • electron capture
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11
Q

Indium-111

Half-life?

Energy?

Production?

Decay?

A
  • 67 hours
  • “medium energy” 173 and 247 (175 and 250 to remember)
  • Cyclotron
  • electron capture
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12
Q

I-131

Half life?

Energy?

Production?

Decay?

A
  • 8 days (~1 week)
  • 364 KeV (~1 year)
  • Nuclear Reactor produced
  • Beta minus decay
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13
Q

Treatment Radionuclide Half-Lives

  • Samarium-153
  • Yttrium-90
  • Radium-223
  • Strontium-89
A
  • Samarium-153 = 46 hours
  • Yttrium-90 = 64 hours (~3 days)
  • Radium-223 (11 days)
  • Strontium-89 (50.5 days; 14 days in bones)
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14
Q

Cardiac Radionuclide Half Lives

  • Rubidium 82
  • N-13
A
  • Rubidium 82 = 75 seconds
  • N-13 = 10 minutes
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