Hair & Nail Disorders Flashcards

0
Q

What are the clinical features of onychomycosis?

A
  • first asymptomatic, usually patient comes in for cosmetic purposes
  • as disease progresses: pain, numbness
  • can interfere with walking, exercise, standing
  • subungal hyperkeratosis
  • onycholysis: white/yellow color
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1
Q

What is onychomycosis?

A
  • fungal infection of nails
  • can involve any part: matrix, nail bed, nail plate
  • can come from direct skin contact or invasion from nearby affected skin (fungus grow in dark moist places, such as feet)
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2
Q

How is onychomycosis diagnosed?

A
  • scraping for KOH (in office)

- nail clipping for PAS stain (sent away)-more applicable if you suspect another nail disease

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3
Q

What is the treatment for onychomycosis?

A
  • topical + oral decreases recurrence rates
  • risk vs. benefit w/ tx–cost, labs, side effects, med interactions
  • topical– generally ineffective, unable to penetrate nail plate: daily application for almost a year
  • oral: most effective– use lamisil (terbinafine): 1 pill/day for 1 month (fingernails), 1 pill/day for 3 months (toenails), but costs a lot of $$, patient must wait until nail grows out to see improvement, labs needed: LFTs baseline and 6 weeks
  • Nail avulsion
  • Laser (? benefit)
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4
Q

What is paronychia?

A

soft tissue infection that occurs around fingernail

  • acute-painful/purulent-caused by STAPH
  • chronic (6+weeks)-swelling, non-purulent-caused by FUNGUS
  • breakdown of nail fold due to cracks, fissures, trauma–allows entry way for organisms
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5
Q

What are the clinical features of paronychia?

A
  • acute: pain, swelling at nail fold, erythema, pus

- chronic: 6+ weeks, erythema, swelling, tenderness at nail fold, nail plate may become thickened and discolored

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6
Q

What is the workup for paronychia?

A
  • bacterial culture
  • KOH smear
  • imaging if osteomyelitis suspected
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7
Q

What is the treatment for paronychia?

A

acute: oral antibiotics, soaks, incise and drain
chronic: topical/oral antifungal, warm soaks

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8
Q

How do you educate patients on paronychia avoidance?

A

avoid nail biting
trim hang nails
trim nails flush to tip
avoid excessive moisture exposure

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9
Q

What is alopecia areata?

A
  • recurrent non scarring alopecia that can affect any hair bearing area
  • scalp, beard, eyebrows (localized 50% involvement)
  • alopecia areata: discrete patches of loss
  • alopecia totalis: entire scalp is bald
  • alopecia universalis: all hair bearing areas of body are bald
  • can affect children and adults
  • benign but cosmetically unappealing
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10
Q

What is the cause of alopecia?

A

unknown

probably autoimmune

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11
Q

What are the clinical features of alopecia areata?

A
  • asymptomatic
  • mild pruritis or burning
  • discrete bald patch with smooth non inflamed underlying skin
  • exclamation hairs are pathognomonic (sign o symptom indicative of a particular disease/condition)
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12
Q

What are exclamation point hairs? (alopecia areata)

A

-not seen in any other type of alopecia, they border new patches of alopecia areata, indicating the patch is expanding

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13
Q

What is the diagnostic evaluation of alopecia areata?

A
  • pull test: pull from the periphery of patch, if hair easily pulls out disease is active and more loss can be expected
  • diagnosis made clinically
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14
Q

What is the treatment for alopecia areata?

A
depends upon extent of disease
topical or intralesional steroids
SADE-immunotherapy
wigs/hair prosthesis
disease unpredictable
change of regrowth great with limited disease, worse with extensive dz
when hair regrows it will be white and fine
no preventative treatment
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15
Q

What is androgenic alopecia?

A

genetically determined patterned alopecia
men+ women
progressive
gradual conversion of terminal hairs–>indeterminate hairs–>vellus hairs
cosmetic concern

16
Q

How do men and women present differently in androgenetic alopecia?

A

men: gradual thinning at temporal hairline: gradual front recession
women: thinning at crown of scalp, may notice widened part

  • no symptoms of pruritus/inflammation
  • increased hair shedding possible

(picture of different classes -class2-class7)

17
Q

What is the workup for androgenetic alopecia?

A
  • labs-thyroid, iron status, hormonal testing (DHEAS and testosterone)
  • scalp biopsy: 2 samples for both horizontal and vertical sectioning
18
Q

What is the treatment for androgenetic alopecia?

A
  • no cure
  • any tx is attempt to maintain not regrow- regrowth is possible not guaranteed
  • treatment=maintenance
  • best to tx early
  • Minoxidil (rogaine)-topical solution–women respond better (2% and 5% strengths)
  • finasteride (propecia)-oral medicine–not for use in females-can produce ambiguous genitalia in fetus
  • surgical treatment: hair transplant
  • wigs
  • course is unpredictable