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clinical medicine > Derm > Flashcards

Derm Flashcards

0
Q

What kind of barrier is the skin?

A

Physical and immunologic

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1
Q

Largest organ of the body?

A

Skin

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2
Q

What is the skin responsible for?

A

Temperature regulation, insulation and sensation

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3
Q

Skin components include?

A

Epidermis, dermis, sweat glands, oil glands, hair, and nails, subcutaneous fat

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4
Q

Layers of the skin starting at the bottom “basement”?

A

Basal cell, stratum spinosum, stratum granulosum, stratum corneum, epidermis (includes melanocytes and langerhans cells)

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5
Q

What are the undifferentiated proliferating cells?

A

Basal cells

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6
Q

What is above the basal cell layer?

A

Stratum spinosum

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7
Q

What does the stratum spinosum contain?

A

Keratinocytes which produce keratin

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8
Q

Above the stratum granulosum? What happens here?

A

Stratum granulosum. Cells differentiate here and acquire more keratin and become FLATTER.

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9
Q

Found in the stratum granulosum, What is the cement that holds together the cells of the stratum corneum.

A

Polysaccharides, glycoproteins, and lipids.

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10
Q

Top layer of the epidermis?

A

Stratum corneum

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11
Q

What layer of the epidermis is the major physical barrier?

A

Stratum corneum

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12
Q

What do the cells in the stratum corneum look like?

A

Large, flat, filled with keratin. Cells are stacked in vertical layers and vary in thickness depending on location.

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13
Q

How many layers of the stratum corneum cells?

A

15-25 layers on most surfaces

100 layers on palms and soles

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14
Q

Cells divide in what layer?

A

Basal cell layer

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15
Q

Keratinization occurs in which layers

A

Stratum spinosum, granulosum, corneum.

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16
Q

What are the pigment producing cells found in the basal cell layer? These cells provide protection from ultraviolet radiation.

A

Melanocytes

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17
Q

“Soldiers of the skin”

A

Langerhans cells

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18
Q

What cells are derived from bone marrow?

A

Langerhans cells

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19
Q

What cells are identical to tissue macrophages and present antigens to lymphocytes?

A

Langerhans cells

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20
Q

What layer of the skin contains nerves, blood vessels, and appendages?

A

Dermis

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21
Q

What are the ranges in thickness of the dermis?

A

1-4 mm

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22
Q

What are the skin appendages?

A 
Eccrine sweat glands, 
apocrine sweat glands, 
hair follicle, 
sebaceous glands, 
nails
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23
Q

What skin appendage is responsible for regulation of body temp?

A

Eccrine sweat glands

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24
Q

What triggers the eccrine sweat glands?

A

Emotion and thermal stimuli.

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25
Q

How much sweat can the body secrete per day and how is sweat transported?

A

Up to 10 liters per day. Transported by a sweat duct located in the dermis, which then creates a path to the epidermis.

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26
Q

What appendage is responsible for body odor?

A

Apocrine sweat gland

27
Q

What is apocrine sweat glands? Used for and location.

A

No useful purpose
-body odor, odor is caused by bacteria
Glands are located in the axillae and anogenital areas
Apocrine glands are located deep in the dermis and reach the skin surface via the hair follicle.

28
Q

Hair follicle job, location and types?

A

Protective, decorative, and the two types are:

  • vellus-short, fine, light colored.
  • terminal thick, coarse, darkly colored.
29
Q

Hair growth (growth phase?)

A

Anagen phase

30
Q

Hair growth (transition phase?)

A

Catagen phase

31
Q

Hair growth (resting phase)

A

Telogen phase.

32
Q

What are the oil glands?

A

Sebaceous glands

33
Q

What do the sebaceous glands produce? It’s an oily substance.

A

Sebum

34
Q

Where and at what size are sebaceous glands?

A

Located where hair follicles are present and mainly the face and scalp. Size and activity are androgen control. Reach full size at puberty.

35
Q

What are the nails made of?

A

Keratin. Formed from a matrix of dividing epidermal cells. Nails are hard, flat, and lie parallel to the skin. Grow .1 mm per day. Toenails grow at a slower rate.

36
Q

What protects the nail matrix and contains the cuticle?

A

Proximal nail fold

37
Q

What produces the nail plate and lies beneath the proximal nail fold?

A

Nail matrix

38
Q

What does the epithelium of the nail bed adhere to?

A

Nail plate

39
Q

What is the distal edge of the nail?

A

Hyponychium

40
Q

What lies between the dermis and the fascia? And what is its function?

A

Subcutaneous fat.

- insulation, cushion, and energy.

41
Q

History questions of a derm patient?

A

Age, sex, ethnicity. When did the problem start, where did it start, what areas are affected now, does it migrate, does the problem come and go or is it constant, have you had this before, any social contacts with a similar problem or rash, are there any associated symptoms itch or pain, what medications do you take- Rx, prn, Otc, how long have you been on these nmedications, what types of products do you use, any new products, have you seen anyone else for this problem, what treatments did you try and did they help, have you had blood testing done, any biopsies, obtain a past medical history, family history, social history, work duties, hobbies, athletics?

42
Q

What do you need to do a physical exam of the skin?

A

Good eyesight, good lighting, magnifying glass, ruler, tape measurer, look everywhere! Take pictures.

43
Q

When should you refer?

A
  • always get opinion of supervising physician
  • if problem is underlying disease like cancer
  • rare diagnosis
  • surgical referral
44
Q

What does a Macule look like?

A
  • FLAT skin lesion

- different color than surrounding skin

45
Q

What does a Papule look like?

A

Small raised skin lesions

46
Q

What are comedones and what do they look like?

A

Blackheads and whiteheads

Descriptive acne term

47
Q

What is a blister filled with clear fluid that is LESS than .5 cm?

A

Vesicle

48
Q

What is a blister filled with clear fluid that is GREATER than .5 cm?

A

Bullae

49
Q

What is a raised fluid filled lesion that is filled with purulent or cloudy fluid? “Pus inside”

A

Pustule

50
Q

A lesion of dermal edema? (A hive)

A

Wheal

51
Q

Raised marble like.

Diameter and depth greater than .5 cm

A

Nodule

52
Q

Skin defect that completely erodes the epidermis and part of the dermis?

A

Ulcer

53
Q

What happens when people scratch a lot.

It’s a defense mechanism by the skin. Epidermal thickening. Visible and palpable.

A

Lichenification

54
Q

“Skin tag” soft fleshy raised growth

A

Polyp

55
Q

Linear tear in the epidermis

- eczema ( crack that can bleed)

A

Fissure

56
Q

Visibly thickened stratum corneum, dry appearance

A

Scale

57
Q

“Scab” dried liquid on the surface of the skin

Blood, serum, or pus

A

Crust

58
Q

Loss of skin tissue

-sinking in of the skin

A

Atrophy

59
Q

Elevated but lacking significant depth?

Diameter is greater than .5 cm

A

Plaque

60
Q

Enlarged superficial blood vessels

- broken blood vessels at the skin

A

Telangectasia

61
Q

Complete loss of pigment

- color cells of skin die

A

De pigmentation

62
Q

Partial loss of pigment

A

Hypopigmentation

63
Q

Excess pigment

A

Hyperpigmentation

64
Q

Skin tension lines
Useful when performing procedures
Guide to produce the strongest scar and provide a better cosmetic outcome

A

Langer lines

65
Q

Pruitis means?

A

Itching

66
Q

Excoriation means?

A

Picking or scratching

clinical medicine (12 decks)

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