Haemotology 3 - WBCs Flashcards
what is the most abundant WBC?
Neutrophils (50-70% of WBCs)
general term for WBCs
leukocytes
name the 5 types of leukocytes
Neutrophils
Eosinophils
Basophils
Lymphocytes
Monocytes
least abundant leukocyte?
Basophils
what is the common cell that forms 4 of the leukocytes
common myeloid progenitor (which then forms the myeloblast, then basophils, neutrophils, eosinophils and monocytes)
name the common cell that produces lymphocytes
common lymphoid progenitor
main defining feature of leukocytes
has a nucleus
key general roles of WBCs
defend against pathogens
toxin and waste removal
remove damged cells (e.g. RBCs)
common features of all leukocytes: extravasation
can squeeze between endothelial cells to enter surrounding tissue
basically, can migrate out of bloodstream
via process called DIAPEDESIS
common features of all leukocytes: amoeboid movement
develops projections using the cytoplasm to form pseudopodia
psuedopodia are like little legs
use it to move through endothelial lining out of bloodstream into tissues
so it assists extravasation
not only in wbcs, but in others as well
common features of all leukocytes: chemical stimuli
all respond to different chemical stimuli
can also give off chemical stimuli to attract other cells
POSITIVE CHEMOTAXIS
common features of all leukocytes: phagocytosis
only neutrophils, eosinophils and monocytes can do it
what is the normal WBC count range
4-11 x 10^9 /litre blood
no. in blood often an indicator of disease
which of the 5 are granulocytes
neutrophils
eosinophils
basophils
which of the 5 are agranulocytes
lymphocytes
monocytes