Haemostatis Flashcards
Name the 3 phases of Haemostasis
- Vascular phase
- platelet phase
- Coagulation phase
Fill In the general diagram:
Fill in the diagram
What are the 3 steps in phase 1 of the vascular phase?
- Cut triggers vascular spasm
- Endothelial cels contract and expose the basal lamina to blood
- Can slow or stop flow of blood (unlikely)
What do endothelial cells release in step 2 of the vascular phase?
- Chemical Factors
- Local Hormones
What do the chemical factors released by the endothelial cells in the vascular phase stimulate?
- Further smooth muscle contraction
- cell division of:
- endothelial cells
- Fibrocytes
- Smooth muscle cells
- Repair process
What happens in step 3 of the vascular phase?
- Endothelial membrane becomes sticky
What is platelet adhesion?
Attachment of platelets to the sticky endothelial surface, basal laminae and to exposed collagen fibres
How many seconds after injury does the platelet phase begin?
within 15 seconds
What happens in platelet aggregation?
Platelets stick together and form a platelet plug
What are the 3 coagulation phase pathways?
- Extrinsic
- Intrinsic
- Common
Every Injury Counts!
What is the difference between the intrinsic and extrinsic pathways?
Extrinsic pathway is followed if the injury is from an outside source - getting kicked
Intrinsic is followed when the injury is from inside - blood clot etc.
Diagram 1 - fill in the common pathway
Fill in the intrinsic pathway
Fill in the extrinsic pathway
