Haemophilus

Question 1

General characteristics

Answer 1

Small, GN, facultative anaerobes

• rods to coccobacilli
• nonmotile
• oxidase positive
• ferment glucose
• fastidious/sensitive to the environment

Question 2

X and V factor

Answer 2

• X: hematin, not required if grown anaerobically

- V: NAD or NADP (chocolate agar)

Question 3

Haemophilus influenzae

Answer 3

Human respiratory pathogen

Question 4

H. parasuis

Answer 4

Early colonizer of neonatal pigs

• common in swine URT
• requires only V factor (NAD) for growth
• 15 serotypes based on heat stable antigens

Question 5

H. parasuis disease

Answer 5

Sporadic, stress-associated disease in young pigs of conventional herds
- also causes disease outbreaks in non-immune HHS pigs of all ages

Question 6

Glasser’s disease

Answer 6

Systemic disease of H. parasuis in weaned pigs

• fibrous polyserositis, polyarthritis, and meningitis or secondary respiratory infections
• sudden death, neurologic signs, anorexia, lameness, joint swelling, abortion
• high morbidity and mortality in unexposed herds

Question 7

Glasser’s disease pathology

Answer 7

Arthritis, pleuritis, pericarditis, peritonitis, meningitis, polyserotitis, rhinitis, periorchitis

Question 8

H. parasuis can cause _______ without septicemia

Answer 8

Acute bronchopneumonia

- secondary to viral infection

Question 9

H. parasuis virulence factors

Answer 9

• capsular polysaccharide
• fimbriae
• lipoligosaccharide (LOS)
• survives in phagocytic cells

Question 10

H. felis

Answer 10

Isolated form lower respiratory tract of a cat with chronic obstructive pulmonary disease

• common commensal in the feline URT
• opportunistic pathogen = conjunctivitis and URI
• requires CO2 and V factor for growth

Question 11

H. haemoglobinophilus

Answer 11

Normal flora of canine lower urogenital tract

• causes cystitis and neonatal infections
• associated with vaginitis