Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Histology > Haematopoisis > Flashcards

Haematopoisis Flashcards

1
Q

hematopoiesis in the 2nd week of development is by __________

A

Yolk sack

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Hematopoiesis in the 6th week of development is by __________

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hematopoiesis in the 6-8th week until 8th month of development is by ________

A

Spleen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hematopoiesis after birth is by ____________

A

Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Types of bone marrow

A
  1. Red bone marrow .

2. White bone marrow .

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Why we call it ( red bone marrow ) ?

A

Due to large amount of blood and hematopoietic cells .

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Why we call it ( yellow bone marrow ) ?

A

Due to large amount of adipose cells and absence of hematopoietic cells .

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Red bone marrow histology

A
  1. Stroma .
    a. Adventitial reticular cells .
    b. Macrophages .
  2. Hematopoietic cord .
  3. Sinusoidal capillaries .
  4. Adipocytes .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Sinusoidal capillaries histology

A
  1. Diameter is about 45-80um .
  2. Endothelial cells .
  3. Reticular fibers .
  4. Incomplete basal lamina .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The function of bone marrow

A
  1. Blood production .
  2. Rbc destruction .
  3. Immune system ( macrophages & plasma cells )
  4. Storage of Fe .
  5. Production of cytokines & growth factors .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Myeloid tissue if responsible of production of :

A
  1. Erythrocytes .
  2. Platelets .
  3. Granulocytes .
  4. Monocytes .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lymphatic tissue organs

A
  1. Thymus .
  2. Lymph nodes .
  3. Spleen .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

All blood cells are arise from

A

Hemocytoblast ( pluripotent stem cell )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Hemocytoblast description

A
  1. 15-20um in diameter .
  2. Deep basophilic cytoplasm ( a lot of ribosomes ) .
  3. Rounded or oval nucleus contain 2-5 nucleoli .
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Erythropoiesis is regulated by

A

Erythropoietin which secreted by kidney .

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Erythropoietic cells lack of nucleoli

A
  1. Polychromatophilic erythroblast .
  2. Normoblast .
  3. Reticulocyte .
  4. Mature rbc .
17
Q

Erythropoietic cells don’t have nucleus

A
  1. Reticulocyte .

2. Mature rbc .

18
Q

Erythropoietic cells have basophilic cytoplasm

A
  1. Proerythroblast .

2. Basophilic erythroblast .

19
Q

Erythropoietic cells have acidophilic cytoplasm

A
  1. Normoblast .
  2. Reticulocyte .
  3. Mature rbc .
20
Q

What are the changes happen through erythropoiesis ?

A
  1. Decrease in the size from 14 to 7.5 .
  2. Lack of nucleus gradually .
  3. Lack of nucleolus gradually .
  4. Cytoplasm converted from baso to acidophilic .
  5. Lack of ribosome & mitochondria .
  6. Increase in amount of Hb .
21
Q

Large nucleus ( 80% of cell volume )

A

Proerythroblast

22
Q

Chromatin arranged as ( clock face ) / irregular

A

Basophilic erythroblast

23
Q

Chromatin arranged as ( checker board ) /regular

A

Polychromatophilic erythroblast

24
Q

Round , small & dense chromatin / about 1/4 of cell volume

A

Normoblast ( orthrochromatophilic erythroblast )

25
Q

Contains only Hb

A

Mature rbc

26
Q

Filled with Hb & cluster of ribosomes

A

Reticulocyte

27
Q

Hb starts to appear

A

Basophilic erythroblast

28
Q

Does not contain Hb

A

Proerythroblast

29
Q

Megakaryoblast description

A
  1. 25-30um .
  2. Oval nucleus .
  3. Homogenous & basophilic cytoplasm .
  4. Many mitosis division .
  5. Nucleus is multilobulated .
30
Q

Megacaryocyte description

A
  1. 30-100um in diameter .
  2. Multilobular nucleus .
  3. Slightly acidophilic .
  4. Few ribosomes , smooth & RER .
31
Q

Proplatelets

A

Long & branched processes which penetrate the sinusoidal endothelium to lie within circulation .

32
Q

Granulopoietic cells have no nucleoli

A
  1. Metamyelocyte .
  2. Band cell .
  3. Mature granular wbc .
33
Q

Granulopoietic cell has no granules

A

Myeloblast

34
Q

What is the changes during granulopoiesis

A
  1. Decrease in diameter .
  2. Nucleus ( round —> oval —> kidney —> horse shoe —> curved rode —> lobulated .
  3. Condensing of chromatin .
  4. Nucleoli disappear gradually .
  5. Basophilic cytoplasm —> pale bluish - pink .
  6. Formation of granules .
    Decrease in organelles ( RER , golgi , mitochondria & ribosome ) .
35
Q

Promonocyte description

A
  1. 16-18um in diameter .
  2. Oval or kidney & eccentric nucleus .
  3. Basophilic cytoplasm .
  4. No specific granules .
  5. Large amount of organelles .
36
Q

Lymphoblast description

A
  1. Large round cell .
  2. Basophilic cytoplasm .
  3. No granules .
  4. Rounded nucleus .
  5. Dense chromatin .
  6. 2-3 nucleoli .
37
Q

Polylymphocte

A
  1. Smaller than lymphoblast .
  2. Basophilic cytoplasm .
  3. Dense chromatin .
  4. Nucleoli can not be seen .

Histology (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions