Haematopoiesis

Question 1

Case of focal haematopoietic hyperplasia of a VB presenting as a psuedotumour and back pain
Biopsy gave result of chronic myeloproliferative disease but diagnosis excluded by WHO criteria
Regarded as a late reactive process after trauma

Answer 1

Detti et al., (2013)`

Question 2

Is rare in thalassaemia to get extra-medullary haematopoiesis affecting the vertebral column

Answer 2

Aydmgoz et al., (1997)

Question 3

Thalasaemmia intermedia affecting the spinal epidural space and causing spinal cord compression
Radiotheraphy decreased the size of the lesion and symptoms went away

Answer 3

Aydmgoz et al., (1997)

Question 4

Adults with B thalassaemia frequently have low BMD, fractures and bone pain
Typically bone marrow expansion involves face and limbs but can effect spine

Answer 4

Vogiatzi et al., (2009)

Question 5

Yolk sac contributes to adult haematopoiesis

Answer 5

Samokhvaleva et al., (2007)