Haematology practical 1

Question 1

Basic tests investigations

Answer 1

1. Full blood Count
2. PTT
3. PT

Question 2

Coagulation cascade
Other names for factor 1 and 2

Question 3

Vitamin K dependent factors

Answer 3

Factor:2,7,9 and 10

Question 4

Case 1:

A well looking 5 year old girl,presents with 2 days only petechiae on her arm and in her mouth
Viral infection 3 weeks prior
No family history ,fever,lymphadenophathy,

Qs:
1,
2.
3.

Question 5

Case 1: Differential diagnosis for petechiae in children

• Petechiae(<2mm,pinpoint)
  Purpura(>2mm,pinhead)
  Ecchimoses (Bruising)

Answer 5

1. Immu e mediated thrombocytopenia purpura
2. Meningococcus
3. Aplastic anemia
4. Leukemia
5. HIV
   6.HSP

Question 6

Case 1: Screening blood tests

Answer 6

PT and PTT normal
FBC:

Question 7

Diagnosis : Immune Mediated thrombocytopenia purpura

Answer 7

-Most common thrombocytopenia in children
- Age: 2-5 yrs
Boys and girls
-well child

Question 8

Immune thrombocytopenia ranges

Question 9

Case 2

Question 10

Vitamin K deficiency of newborn

Answer 10

• pathophysiology
  Natural Vit K is synthesized by the intestinal flora
  Fat soluble
  Requires bile for absorption
  Not stored in body
  Liver ….

Question 11

Most common inherited bleeding disoder

Question 12

Most common acquired bleeding disorder

Question 13

Vitamin K dependent Factors

Question 14

When a child is sick which other 2 screening tests do you include

Answer 14

Fibrinogen
D-dimers