Haematology basics Flashcards
What is blood?
A tissue consisting of cells suspended in a liquid
What are the three types of cell in blood?
RBC
WBC
Platelet
What are the two lineages a multipotent progenitor can go down
Myeloid
Lymphoid
What are myeloid cells?
Erythrocytes
Platelets
Macrophages
Granulocytes
What are lymphoid cells?
T cells
B cells
NK cells
How can you identify primitive precursor cells (hint, can’t be done visually as all look the same)?
Immunophenotyping- Expression profile of proteins (antigens) on the surface of cells
Bio-assey- Culture in vitro and show lineage of progeny in different growth conditions
What is another name for a macrophage?
Histiocyte
What does MCH stand for?
Mean corpuscular hemoglobin
What is the MCH a measure of?
How much Hb is in a cell.
What is MCV?
Mean cell volume
What is MCV a measure of?
Volume of RBC.
What is thrombocytosis?
Too many platelets
What affect does testosterone have on RBC production?
Increases it
