Haematology Flashcards

1
Q

What tumour is associated with myasthenia gravis

A

Thymoma

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2
Q

How many weeks before surgery should you stop the COCP

A

4 week

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3
Q

Burkitts lymphoma tumour marker

A

C-myc

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4
Q

Type of anaemia in sickle cell and blood cells associated with it

A

Normochromic normocytic

Reticulocytes

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5
Q

Cells associated with G6PD deficiency

A

Bite and blister cells

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6
Q

What drugs should you avoid in G6PD

A

Sulph- drugs

Glipizide

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7
Q

Ethnicity associated with benign neutropenia

A

Black/Caribbean

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8
Q

MOA of dabigatran

A

Direct thrombin inhibitor

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9
Q

Clinical finding in CML

A

Splenomegaly

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10
Q

Investigation for autoimmune haemolytic anaemia

A

Positive coombs

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11
Q

What genetic condition is malaria associated with

A

G6PD deficiency

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12
Q

2 cells found in coeliac disease

A

Howell Jolly Bodies
Target cells
Reduced spleen

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13
Q

Most common bleeding disorder

A

Von Willebrand disease

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14
Q

4 blood test findings in DIC

A

Reduced platelets
Increased PT and APTT
Fibrinogen can be increased or decreased

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15
Q

Diagnosis of sickle cell

A

Hb electrophoresis

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16
Q

Drug which can cause renal impairment

A

Apixiban

17
Q

What does Tamoxifen increase the risk of?

A

VTE

18
Q

Cells found in CLL

A

smear / smudge cells

19
Q

Blood test fining in haemophilia B

A

Increased APTT

association with heparin and antiphospholipid?

20
Q

4 histological findings in Hodgkins lymphoma

A

Reed sternberg cells
Mirror image nuclei
Large multinucleate cells
Eosinophilic nuclei

21
Q

Poor prognostic indicator in a transfusion reaction

A

Hypotension

22
Q

2 conditions associated with polycythaemia

A

Stroke

AML

23
Q

If there is a negative scan for DVT

A

Stop anticoagulants

Repeat in 1 week

24
Q

Clinical feature of CLL

A

Recurrent infections

25
Q

Histology of myelofibrosis

A

Teardrop cells

26
Q

2 clinical features and 2 investigations for autoimmune haemolytic anaemia

A

Jaundice and anaemia
Positive coombs
Direct antiglobulin

27
Q

Medication in VW factor

A

Desmopressin

28
Q

Risk with sickle cell and parvovirus

A

Aplastic crisis

29
Q

Blood products needed in graft vs host disease

A

Irradiated blood products

30
Q

Treatment of neutropenic sepsis

A

IV piperacillin and taxobactam

31
Q

Side effect of allopurinol

A

Reduced tumour lysis (chemo risk)

32
Q

3 things that happen in a sickle cell crisis

A

Aplastic
Reduced reticulocytes
Sequestration increases

33
Q

Finding in thalassaemia major

A

HbA2 increases

34
Q

What Hb is in sickle cell?

A

HbS

35
Q

Myeloma features

A

hyperCalcaemia
Renal failure
Anaemia
Bone disease

36
Q

Myeloma on a film

A

Roleaux

37
Q

3 blood test features of anaemia of chronic disease

A

Reduced Fe
Reduced TiBC
Increased ferritin

38
Q

Sickle cell + bilateral lung infiltrates

A

Acute sickle cell syndrome