Haematology

Question 1

What tumour is associated with myasthenia gravis

Answer 1

Thymoma

Question 2

How many weeks before surgery should you stop the COCP

Answer 2

4 week

Question 3

Burkitts lymphoma tumour marker

Answer 3

C-myc

Question 4

Type of anaemia in sickle cell and blood cells associated with it

Answer 4

Normochromic normocytic

Reticulocytes

Question 5

Cells associated with G6PD deficiency

Answer 5

Bite and blister cells

Question 6

What drugs should you avoid in G6PD

Answer 6

Sulph- drugs

Glipizide

Question 7

Ethnicity associated with benign neutropenia

Answer 7

Black/Caribbean

Question 8

MOA of dabigatran

Answer 8

Direct thrombin inhibitor

Question 9

Clinical finding in CML

Answer 9

Splenomegaly

Question 10

Investigation for autoimmune haemolytic anaemia

Answer 10

Positive coombs

Question 11

What genetic condition is malaria associated with

Answer 11

G6PD deficiency

Question 12

2 cells found in coeliac disease

Answer 12

Howell Jolly Bodies
Target cells
Reduced spleen

Question 13

Most common bleeding disorder

Answer 13

Von Willebrand disease

Question 14

4 blood test findings in DIC

Answer 14

Reduced platelets
Increased PT and APTT
Fibrinogen can be increased or decreased

Question 15

Diagnosis of sickle cell

Answer 15

Hb electrophoresis

Question 16

Drug which can cause renal impairment

Answer 16

Apixiban

Question 17

What does Tamoxifen increase the risk of?

Answer 17

VTE

Question 18

Cells found in CLL

Answer 18

smear / smudge cells

Question 19

Blood test fining in haemophilia B

Answer 19

Increased APTT

association with heparin and antiphospholipid?

Question 20

4 histological findings in Hodgkins lymphoma

Answer 20

Reed sternberg cells
Mirror image nuclei
Large multinucleate cells
Eosinophilic nuclei

Question 21

Poor prognostic indicator in a transfusion reaction

Answer 21

Hypotension

Question 22

2 conditions associated with polycythaemia

Answer 22

Stroke

AML

Question 23

If there is a negative scan for DVT

Answer 23

Stop anticoagulants

Repeat in 1 week

Question 24

Clinical feature of CLL

Answer 24

Recurrent infections

Question 25

Histology of myelofibrosis

Answer 25

Teardrop cells

Question 26

2 clinical features and 2 investigations for autoimmune haemolytic anaemia

Answer 26

Jaundice and anaemia
Positive coombs
Direct antiglobulin

Question 27

Medication in VW factor

Answer 27

Desmopressin

Question 28

Risk with sickle cell and parvovirus

Answer 28

Aplastic crisis

Question 29

Blood products needed in graft vs host disease

Answer 29

Irradiated blood products

Question 30

Treatment of neutropenic sepsis

Answer 30

IV piperacillin and taxobactam

Question 31

Side effect of allopurinol

Answer 31

Reduced tumour lysis (chemo risk)

Question 32

3 things that happen in a sickle cell crisis

Answer 32

Aplastic
Reduced reticulocytes
Sequestration increases

Question 33

Finding in thalassaemia major

Answer 33

HbA2 increases

Question 34

What Hb is in sickle cell?

Answer 34

HbS

Question 35

Myeloma features

Answer 35

hyperCalcaemia
Renal failure
Anaemia
Bone disease

Question 36

Myeloma on a film

Answer 36

Roleaux

Question 37

3 blood test features of anaemia of chronic disease

Answer 37

Reduced Fe
Reduced TiBC
Increased ferritin

Question 38

Sickle cell + bilateral lung infiltrates

Answer 38

Acute sickle cell syndrome